• The fungal UPR: A regulatory hub for virulence traits in the mold pathogen <i>Aspergillus fumigatus</i>
  • Association between spoligotype-VNTR types and virulence of <i>Mycobacterium bovis</i> in cattle
  • Extracellular enzyme profiling of <em>Stenotrophomonas maltophilia</em> clinical isolates
  • Structural features and mechanism of translocation of non-LTR retrotransposons in <em>Candida albicans</em>
  • The unfolded protein response (UPR) pathway in <em>Cryptococcus</em>

 The fungal UPR: A regulatory hub for virulence traits in the mold pathogen Aspergillus fumigatus

Karthik Krishnan and David S Askew

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Association between spoligotype-VNTR types and virulence of Mycobacterium bovis in cattle

Sergio Garbaccio, Analía Macias, Ernesto Shimizu, Fernando Paolicchi, Natalia Pezzone, Gabriel Magnano, Laura Zapata, Alejandro Abdala, Hector Tarabla, Maite Peyru, Karina Caimi, Martín Zumárraga, Ana Canal and Angel Cataldi

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Extracellular enzyme profiling of Stenotrophomonas maltophilia clinical isolates

Renjan Thomas, Rukman Awang Hamat and Vasanthakumari Neela

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 Structural features and mechanism of translocation of non-LTR retrotransposons in Candida albicans

Jingchen Jiang, Liuya Zhao, Lan Yan, Lulu Zhang, Yingying Cao, Yan Wang, Yuanying Jiang, Tianhua Yan and Yongbing Cao

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 The unfolded protein response (UPR) pathway in Cryptococcus

Seon Ah Cheon, Kwang-Woo Jung, Yong-Sun Bahn and Hyun Ah Kang

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Current Issue

Virulence

April 1, 2014

Volume 5, Issue 3

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About the cover image
An overview of the main methods of novel gene discovery using metagenomics. A sample from the environment of interest (e.g., soil, human gastrointestinal tract, or ocean) is collected (A), total metagenomic DNA is isolated directly or indirectly from the sample either by harsh or gentle lysis (B); metagenomic DNA is subsequently subjected to sequence-based analysis (C). Functional metagenomics (D) involves the creation of a small- or large-insert library using a specific type of vector (plasmid, fosmid, cosmid, or bacterial artificial chromosome [BAC]). Novel genes are discovered using sequence-based or functional metagenomic strategies, or a combination of both (E). For more information, see Culligan et al., in this issue.

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This year we plan to publish several Special Foci on timely and interesting topics relevant to host-pathogen interactions. The appearance of your research paper in the context of a series of Reviews written by experts in the field will increase its visibility and round out these special issues. Please contact the Editor-in-Chief with suggestions for future Special Foci.

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Editors-in-Chief

Eleftherios Mylonakis MD, PhD, FIDSA
Warren Alpert Medical School
of Brown University