RsaOG, a new Staphylococcal family of highly transcribed non-coding RNA

 Abstract

The expression of trans-acting small RNAs in firmicutes has been poorly documented to date. This gap is being filled quickly in the genus Staphylococcus, which is both a model firmicute and an important human pathogen. Here we analyse RsaOG, a novel small RNA family specific to Staphylococcus and highly transcribed. This well conserved element, first discovered in a computational screen, was precisely mapped in the genome by RACE mapping and the identification of a putative transcriptional promoter. The proposed secondary structure presents two highly conserved unpaired sequences, part of which can form a pseudoknot. We suggest a possible involvement of the remaining conserved single stranded region in trans regulatory interactions.

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Pages
116 - 119
doi
10.4161/rna.7.2.10925
Type
RNA Families
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RsaOG, a new Staphylococcal family of highly transcribed non-coding RNA