Aging: ROS or TOR

 Abstract

It is widely believed that aging is caused by the accumulation of random molecular damage due to reactive oxygen species (ROS). Here I discuss evidence for and against the ROS theory. Remarkably, even supporting evidence has an alternative explanation, consistent with the model that aging is driven by the TOR (target of rapamycin) signaling pathway.

Full Text Options
Article
Metrics
 Share
 Info
Pages
3344 - 3354
doi
10.4161/cc.7.21.6965
Type
Conceptual Review
 Metrics
 Cite This Article
 Permissions
 Permissions
 Reprints
Aging: ROS or TOR