Controlling Stem Cell Proliferation: CKIs at Work

 Abstract

The cyclin-dependent kinase inhibitors or CKIs are well recognized as intrinsic regulators of the cell cycle. Here, we discuss recent data implicating their activity in restraining adult stem cell self-renewal, and the role that proteins regulating CKI expression play in this process.

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1281 - 1285
doi
10.4161/cc.5.12.2806
Type
Perspectives
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Controlling Stem Cell Proliferation: CKIs at Work