Akt1 in Endothelial Cell and Angiogenesis

 Abstract

Akt, also known as Protein kinase B (PKB), regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Akt influences the expression and/or activity of various pro- and anti-angiogenic factors and Akt isoforms (Akt1, Akt2 and Akt3) have been proposed as therapeutic targets for angiogenesis-related anomalies such as cancer and ischemic injury.

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Pages
512 - 518
doi
10.4161/cc.5.5.2538
Type
Perspectives
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Akt1 in Endothelial Cell and Angiogenesis