Commentary
Accelerated vaccine development against emerging infectious diseases
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Volume 8, Issue 7 July 2012
Pages 1010 - 1012
http://dx.doi.org/10.4161/hv.20805
Keywords: emerging infectious diseases, human artificial lymph node, immunoinformatics, immunomics, immunopeptides, immunostimulatory, immunotoxicity, metagenomics, proteomics, self-assembling vaccine
Authors: Pierre R. Leblanc, Jianping Yuan, Tim Brauns, Jeffrey A. Gelfand and Mark C. Poznansky
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- Pierre R. Leblanc
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Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital; Charlestown, MA USA
- Jianping Yuan
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Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital; Charlestown, MA USA
- Tim Brauns
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Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital; Charlestown, MA USA
- Jeffrey A. Gelfand
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Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital; Charlestown, MA USA
- Mark C. Poznansky
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Corresponding author: mpoznansky@partners.org
Vaccine and Immunotherapy Center, Infectious Diseases Medicine, Massachusetts General Hospital; Charlestown, MA USA
Abstract:
Emerging and re-emerging infectious diseases represent a major challenge to vaccine development since it involves two seemingly contradictory requirements. Rapid and flexible vaccine generation while using technologies and processes that can facilitate accelerated regulatory review. Development in the “-omics” in combination with advances in vaccinology offer novel opportunities to meet these requirements. Here we describe how a consortium of five different organizations from academia and industry is addressing these challenges. This novel approach has the potential to become the new standard in vaccine development allowing timely deployment to avert potential pandemics.
Received: May 13, 2012; Accepted: May 20, 2012; Published Online: July 1, 2012
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