Review
New insights into rotavirus vaccines
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Pages 1022 - 1028
http://dx.doi.org/10.4161/hv.20295
Keywords: intussusception, post-marketing surveillance, rotavirus, rotavirus vaccines, safety
Authors: Chiara Mameli, Valentina Fabiano and Gian Vincenzo Zuccotti
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Abstract:
Rotavirus vaccines have shown to be effective and well tolerated in clinical trials. However it’s crucial to point out that immunization occurs in “real-word” conditions different from ideal clinical trial settings. Thus, the impact of rotavirus vaccines in terms of effectiveness and safety needs to be evaluated in real-world conditions. Post-licensure data regarding vaccine impact, effectiveness and safety under routine use are now available and provide a “real-world view.”
Received: February 25, 2012; Accepted: April 8, 2012; Published Online: August 1, 2012
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