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Special Focus: Therapeutic RNAs

Aptamers and aptamer targeted delivery

Amy C. Yan and Matthew Levy

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When aptamers first emerged almost two decades ago, most were RNA species that bound and tagged or inhibited simple target ligands.  Very soon after, the ‘selectionologists’ developing aptamer technology quickly realized more potential for the aptamer.  In recent years, advances in aptamer techniques have enabled the use of aptamers as small molecule inhibitors, diagnostic tools and even therapeutics.  Aptamers are now being employed in novel applications.  We review, herein, some of the recent and exciting applications of aptamers in cell-specific recognition and delivery.

Authors

Amy C. Yan

Department of Biochemistry Albert Einstein College of Medicine

Matthew Levy Corresponding author: mattlevy@aecom.yu.edu

Department of Biochemistry Albert Einstein College of Medicine

This is an open-access article

 Download PDF

If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.