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How Arginine-Rich Domains Coordinate mRNA Maturation Events
Katherine S. Godin and Gabriele Varani
volume 4 | issue 2
april/may/june 2007Pages: 69 - 75
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Maturation of RNA is highly regulated from transcription to the post-transcriptional processing and localization to specific cellular compartments. The complexes that contribute to these events are in many cases well understood; however, many of the protein factors that coordinate and regulate these RNA processing events remain poorly characterized. Among them are arginine-rich domains, most commonly sequences rich in arginine/serine (RS domains) or arginine/glycine/glycine (RGG boxes), that often appear among factors and complexes involved in RNA processing. They are emerging as key yet poorly understood players in the assembly and coupling of RNA processing events.
Authors
Katherine S. Godin
University of Washington; Seattle, WA
Gabriele Varani
University of Washington; Seattle, WA