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Point of View
HuR: Post-Transcriptional Paths to Malignancy
Isabel López de Silanes, Ashish Lal, Myriam Gorospe
volume 2 | issue 1
january/february/march 2005Pages: 11 - 13
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The RNA-binding protein HuR regulates the stability and translation of target mRNAs. While no HuR mutations have been found in cancer, a link between HuR and malignant transformation has been suggested in cancers of the breast, colon, lung, and ovary. We describe a paradigm consistent with a central role of HuR in oncogenesis.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.