Recommend Plant Signaling & Behavior (PS&B) to your librarian for 2008. Download form here.

PS&B is the official journal of the Society for Plant Neurobiology. Full membership ($60 annually) and student membership ($30 annually) include online access to the journal. Click here to join.

Email this page

Print this page

Article Addendum

NUA Activities at the Plant Nuclear Pore

Xianfeng Morgan Xu, Annkatrin Rose and Iris Meier

volume 2 | issue 6

november/december
Pages: 553 - 555

Purchase article for $19

Subscribe to this journal for $79/year

» Log in

NUA (Nuclear Pore Anchor), the Arabidopsis homolog of Tpr (Translocated Promoter Region), is one of the few nuclear pore proteins conserved between animals, yeast and plants. In the May issue of The Plant Cell, we report that null mutants of NUA show a pleiotropic, early flowering phenotype accompanied by changes in SUMO and RNA homeostasis. We have shown that the early flowering phenotype is caused by changed abundances of flowering time regulators involved in several pathways. Arabidopsis nua mutants phenocopy mutants lacking the ESD4 (Early in Short Days 4) SUMO protease, similar to mutants of their respective yeast homologs. However, in contrast to the comparable yeast mutants, ESD4 does not appear to be delocalized from the nuclear pore in nua mutants. Taken together, our experimental data suggests a role for NUA in controlling mRNA export from the nucleus as well as SUMO protease activity at the nuclear pore, comparable but not identical to its homologs in other eukaryotes. Furthermore, characterization of NUA illustrates a potential link at the nuclear pore between SUMO modification, RNA homeostasis and plant developmental control.

Authors

Xianfeng Morgan Xu

Department of Plant Cellular and Molecular Biology and Plant Biotechnology Center, Ohio State University, Columbus, Ohio USA

Annkatrin Rose

Department of Biology, Appalachian State University, Boone, North Carolina USA

Iris Meier