Table of Contents
Volume 2, Issue 1
January/February 2010
Pages 1 - 105
Editorial
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mAb therapeutic products and risk management
Janice M. Reichert
Pages 1 - 2
Mini-Review
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Canakinumab
Eugen Dhimolea
Pages 3 - 13
Review
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Evolution of anti- CD20 monoclonal antibody therapeutics in oncology
Open Access Article
Ezogelin Oflazoglu and Laurent P. Audoly
Pages 14 - 19
Reports
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A dual-targeting PDGFRβ/VEGF-A molecule assembled from stable antibody fragments demonstrates anti-angiogenic activity in vitro and in vivo
Robert Mabry, Debra G. Gilbertson, Amanda Frank, Tuyen Vu, Dan Ardourel, Craig Ostrander, Brenda Stevens, Susan Julien, Secil Franke, Brent Meengs, Jennifer Brody, Scott Presnell, Nels B. Hamacher, Megan Lantry, Anitra Wolf, Tom Bukowski, Robert Rosler, Cindy Yen, Monica Anderson-Haley, Kenneth Brasel, Qi Pan, Hank Franklin, Penny Thompson, Mike Dodds, Sara Underwood, Scott Peterson, Pallavur V. Sivakumar and Mark Snavely
Pages 20 - 34
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Differential effects of IL-2 and IL-21 on expansion of the CD4+CD25+Foxp3+ T regulatory cells with redundant roles in natural killer cell mediated antibody dependent cellular cytotoxicity in chronic lymphocytic leukemia
Aruna Gowda, Asha Ramanunni, Carolyn Cheney, Darlene Rozewski, Wayne Kindsvogel, Amy Lehman, David Jarjoura, Michael Caligiuri, John C. Byrd and Natarajan Muthusamy
Pages 35 - 41
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Cold denaturation of monoclonal antibodies
Kristi L. Lazar, Thomas W. Patapoff and Vikas K. Sharma
Pages 42 - 52
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Neutralizing epitopes of the SARS-CoV S-protein cluster independent of repertoire, antigen structure or mAb technology
Open Access Article
Jody D. Berry, Kevin Hay, James M. Rini, Meng Yu, Linfa Wang, Francis A. Plummer, Cindi R. Corbett and Anton Andono
Pages 53 - 66
Brief Reports
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Target mediated disposition of T84.66, a monoclonal anti-CEA antibody: Application in the detection of colorectal cancer xenografts
Shweta R. Urva and Joseph P. Balthasar
Pages 67 - 72
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Oligomeric forms of single chain immunoglobulin (scIgG)
Thomas Schirrmann, Christian Menzel, Michael Hust, Jessica Prilop, Thomas Jostock and Stefan Dübel
Pages 73 - 76
Point of View
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Antibody fragments: Hope and hype
Aaron L. Nelson
Pages 77 - 83
Editor's Corner
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Antibodies to watch in 2010
Janice M. Reichert
Pages 84 - 100
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Note of appreciation to reviewers
Janice M. Reichert
Pages 101 - 103
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Upcoming meetings
Janice M. Reichert
Pages 104 - 105