Table of Contents

Volume 4, Issue 1

  January/February 2012

  Pages 1 - 131

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EDITORIAL

Open Access Article

Which are the antibodies to watch in 2012?

Janice M. Reichert
Pages 1 - 3
http://dx.doi.org/10.4161/mabs.4.1.18719





MEETING REPORT

Open Access Article

World Bispecific Antibody Summit, September 27–28, 2011, Boston, MA

Eugen Dhimolea and Janice M. Reichert
Pages 4 - 16
http://dx.doi.org/10.4161/mabs.4.1.18821





REVIEW

Disulfide bond structures of IgG molecules: Structural variations, chemical modifications and possible impacts to stability and biological function

Hongcheng Liu and Kimberly May
Pages 17 - 23
http://dx.doi.org/10.4161/mabs.4.1.18347





REPORTS

Open Access Article

Analysis of host-cell proteins in biotherapeutic proteins by comprehensive online two-dimensional liquid chromatography/mass spectrometry

Catalin Doneanu, Alex Xenopoulos, Keith Fadgen, Jim Murphy, St. John Skilton, Holly Prentice, Martha Stapels and Weibin Chen
Pages 24 - 44
http://dx.doi.org/10.4161/mabs.4.1.18748


A recombinant triplebody with specificity for CD19 and HLA-DR mediates 
preferential binding to antigen double-positive cells by dual-targeting

Ingo Schubert, Christian Kellner, Christoph Stein, Markus Kügler, Michael Schwenkert, Domenica Saul, Bernhard Stockmeyer, Christian Berens, Fuat S. Oduncu, Andreas Mackensen and Georg H. Fey
Pages 45 - 56
http://dx.doi.org/10.4161/mabs.4.1.18498


Immunotoxins constructed with chimeric, short-lived anti-CD22 monoclonal antibodies induce less vascular leak without loss of cytotoxicity

Xiao-yun Liu, Laurentiu M. Pop, John Schindler and Ellen S. Vitetta
Pages 57 - 68
http://dx.doi.org/10.4161/mabs.4.1.18348


Generation and characterization of human anti-human IL-21 neutralizing monoclonal antibodies

Mark F. Maurer, Ursula Garrigues, Stephen R. Jaspers, Brent Meengs, Mark W. Rixon, Brenda L. Stevens, Kenneth B. Lewis, Susan H. Julien, Thomas R. Bukowski, Anitra C. Wolf, Nels B. Hamacher, Mark Snavely and Stacey R. Dillon
Pages 69 - 83
http://dx.doi.org/10.4161/mabs.4.1.18713


Analytical characterization of ch14.18: A mouse-human chimeric disialoganglioside-specific therapeutic antibody

Gopalan Soman, Abraham T. Kallarakal, Dennis Michiel, Xiaoyi Yang, Nirmala Saptharish, Hengguang Jiang, Steve Giardina, John Gilly and George Mitra
Pages 84 - 100
http://dx.doi.org/10.4161/mabs.4.1.18566


Subcutaneous bioavailability of therapeutic antibodies as a function 
of FcRn binding affinity in mice

Rong Deng, Y. Gloria Meng, Kwame Hoyte, Jeff Lutman, Yanmei Lu, Suhasini Iyer, Laura DeForge, Frank-Peter Theil, Paul J. Fielder and Saileta Prabhu
Pages 101 - 109
http://dx.doi.org/10.4161/mabs.4.1.18543


Tolerability, pharmacokinetics and pharmacodynamics of CMAB007, a humanized anti-immunoglobulin E monoclonal antibody, in healthy Chinese subjects

Bo Zhou, Birong Lin, Jing Li, Weizhu Qian, Sheng Hou, Dapeng Zhang, Geng Kou, Bohua Li, Hao Wang, Yongchuan Chen and Yajun Guo
Pages 110 - 119
http://dx.doi.org/10.4161/mabs.4.1.18349


New developments in malaria diagnostics: Monoclonal antibodies against Plasmodium dihydrofolate reductase–thymidylate synthase, heme detoxification protein and glutamate rich protein

Johanna H. Kattenberg, Inge Versteeg, Stephanie J. Migchelsen, Iveth J. González, Mark D. Perkins, Petra F. Mens and Henk D.F.H. Schallig
Pages 120 - 126
http://dx.doi.org/10.4161/mabs.4.1.18529





EDITOR'S CORNER

Open Access Article

2012 upcoming meetings

Janice M. Reichert
Pages 127 - 128
http://dx.doi.org/10.4161/mabs.4.1.18718


Open Access Article

Note of appreciation to reviewers

Janice M. Reichert
Pages 129 - 131
http://dx.doi.org/10.4161/mabs.4.1.18717