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Research Papers

Drosophila Polymorphism Database (DPDB)
A Portal for Nucleotide Polymorphism in Drosophila

Sònia Casillas, Raquel Egea, Natalia Petit, Casey M. Bergman and Antonio Barbadilla

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As a growing number of haplotypic sequences from re-sequencing studies are now accumulating for Drosophila in the main primary sequence databases, collectively they can now be used to describe the general pattern of nucleotide variation across species and genes of this genus. The Drosophila Polymorphism Database (DPDB) is a secondary database that provides a collection of all well-annotated polymorphic sequences in Drosophila together with their associated diversity measures and options for re-analysis of the data that greatly facilitate both multi-locus and multi-species diversity studies in one of the most important group of model organisms. Here we describe the state-of-the-art of the DPDB database and provide a step-by-step guide to all its searching and analytic capabilities. Finally, we illustrate its usefulness through selected examples. DPDB is freely available at http://dpdb.uab.cat.

Authors

Sònia Casillas

Universitat Autn006f006da de Barcelona

Raquel Egea

Universitat Autònoma de Barcelona

Natalia Petit

Universitat Autònoma de Barcelona

Casey M. Bergman

University of Manchester

Antonio Barbadilla

Universitat Autònoma de Barcelona

This is an open-access article

 Download PDF

If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.