CJC is published 12 times a year.
Sign up for Table of Contents Alerts!
Please note: CJC is published in English and Chinese. Manuscripts are published online prior to printing. The citation will change as volume, issue and page numbers are finalized.
Email this page
Print this page
Clinical Research Paper
Correlation of Fever to Infection in Patients with Chemotherapy-Induced Neutropenia
Yan-Ping Ruan and Wen-Ying Zhang
volume 27 | issue 8
August 2008Pages: 177 - 179
Subscribe to this journal for $0/year
BACKGROUND & OBJECTIVE: The cancer patients with chemotherapy-induced neutropeina often suffer from fever and infection, but current opinions on the correlation of the fever to infection are controversial. This study aimed to investigate the incidence and correlation of fever and infection in cancer patients with chemotherapy-induced neutropenia. METHODS: Clinical data of 256 in-patients with chemotherapy-induced neutropenia from January to July 2007 were analyzed. The occurrence of fever and infection in these patients were analyzed by using descriptive analysis and agreement test. RESULTS: Of the 256 patients, 100 (39.1%) suffered from fever, and 42 (16.4%) experienced infection. The temperature of febrile patients was (39.0 ± 0.64)°C. The main sites of infection were the pharynx (42.9%), oral cavity (21.4%) and low respiratory tract (14.3%). The consistency rate was 0.75 between fever and infection (Kappa = 0.414, p < 0.001). CONCLUSION: The incidence of fever and infection in cancer patients with chemotherapy-induced neutropenia are high with a moderate agreement between fever and infection.
Authors
Yan-Ping Ruan
Zhejiang Provincial Cancer Hospital
Wen-Ying Zhang
Zhejiang Provincial Cancer Hospital