Article Addendum

Why is intelligence correlated with semen quality? Biochemical pathways common to sperm and neuron function and their vulnerability to pleiotropic mutations

Volume 2, Issue 5   September/October 2009
Pages 385 - 387
http://dx.doi.org/10.4161/cib.2.5.8716
Authors: Arand Pierce, Geoffrey Miller, Rosalind Arden and Linda S. Gottfredson

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Abstract:

We recently found positive correlations between human general intelligence and three key indices of semen quality, and hypothesized that these correlations arise through a phenotype-wide ‘general fitness factor’ reflecting overall mutation load.  In this addendum we consider some of the biochemical pathways that may act as targets for pleiotropic mutations that disrupt both neuron function and sperm function in parallel. We focus especially on the inter-related roles of polyunsaturated fatty acids, exocytosis, and receptor signaling.

Article Addendum to:
R Arden, L Gottfredson, GF Miller, A Pierce. Intelligence and semen quality are positively correlated. Intelligence 2009

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