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Authors: Josep-Maria Pujal, Santiago Roura, Ana M. Muñoz-Marmol, Jose-Luis Mate and Antoni Bayes-Genis

Josep-Maria Pujal

ICREC Research Group; Health Sciences Research Institute Germans Trias i Pujol (IGTP); Barcelona, Spain

Santiago Roura

ICREC Research Group; Health Sciences Research Institute Germans Trias i Pujol (IGTP); Barcelona, Spain

Ana M. Muñoz-Marmol

Department of Pathology; Hospital Universitari Germans Trias i Pujol; Barcelona, Spain

Jose-Luis Mate

Department of Pathology; Hospital Universitari Germans Trias i Pujol; Barcelona, Spain

Antoni Bayes-Genis

Corresponding author: abayesgenis@gmail.com
ICREC Research Group; Health Sciences Research Institute Germans Trias i Pujol (IGTP); Barcelona, Spain; Department of Medicine; Autonomous University of Barcelona; Barcelona, Spain; Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN); Sargossa, Spain

Abstract:
The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural phenomenon that initiates the journey of a child’s cells within the mother’s blood and other tissues, we used a new procedure in microscopy imaging generating Large Scale Panoramic Pictures (LSPP). This technique can also be extended to explore a broad diversity of experimental models.

Received: October 10, 2011; Accepted: January 20, 2012

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