Fetal-maternal interface: A chronicle of allogeneic coexistence
Volume 3, Issue 1
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Pages 18 - 23http://dx.doi.org/10.4161/chim.19439
: fetal-maternal interface, fish, microchimerism, placenta, tolerance
Authors: Josep-Maria Pujal, Santiago Roura, Ana M. Muñoz-Marmol, Jose-Luis Mate and Antoni Bayes-Genis View affiliations
The existence of allogeneic cells within an individual has been demonstrated in multiple fields such as hematopoietic stem cell or solid organ transplantation, non-depleted blood transfusions and the most common form which is bidirectional maternal-fetal cell trafficking, whereby cells from the fetus pass through the placental barrier. In order to graphically illustrate this early natural phenomenon that initiates the journey of a child’s cells within the mother’s blood and other tissues, we used a new procedure in microscopy imaging generating Large Scale Panoramic Pictures (LSPP). This technique can also be extended to explore a broad diversity of experimental models.
Received: October 10, 2011; Accepted: January 20, 2012