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Special Focus
Modeling cell migration in 3D: Status and challenges
Rajagopal Rangarajan and Muhammad H. Zaman
Volume 2, Issue 2April/May/June 2008
Pages 106 - 109
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Cell migration is a multi-scale process that integrates signaling, mechanics and biochemical reaction kinetics. Various mathematical models accurately predict cell migration on 2-D surfaces, but are unable to capture the complexities of 3D migration. Additionally, quantitative 3D cell migration models have been few and far between. In this review we look and characterize various mathematical models available in literature to predict cell migration in 3-D matrices and analyze their strengths and possible changes to these models that could improve their predictive capabilities.
Authors
- Rajagopal Rangarajan
- The University of Texas at Austin
- Muhammad H. Zaman
- The University of Texas at Austin
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF
If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.
