Table of Contents

Volume 8, Issue 6

  March 15, 2009

  Pages 797 - 958

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News & Views

• Polyploidy and dysregulated ROS signaling

  Open Access Article

  Siobhan E. Craige and John F. Keaney, Jr.
  Pages 797 - 798

• The long and short of it: A new isoform of TIN2 in the nuclear matrix

  Open Access Article

  Susan Smith
  Pages 797 - 798

• Killing metastasis with engineered bacteria

  Open Access Article

  Sheldon Penman
  Pages 797 - 798

Editor's Corner

• Towards a postmodern synthesis of evolutionary biology

  Eugene V. Koonin
  Pages 799 - 800

Extra Views

• p53 methylation—the Arg-ument is clear

  Stephen T. Durant, Er Chieh Cho and Nicholas B. La Thangue
  Pages 801 - 802

• One renegade cancer stem cell?

  Tijana Borovski, Louis Vermeulen, Martin R. Sprick and Jan Paul Medema
  Pages 803 - 808

• Epigenetic patterns of embryonic and adult stem cells

  Noga Bloushtain-Qimron, Jun Yao, Michail Shipitsin, Reo Maruyama and Kornelia Polyak
  Pages 809 - 817

Perspectives

• Mitotic bookmarking of formerly active genes: Keeping epigenetic memories from fading

  Kevin D. Sarge and Ok-Kyong Park-Sarge
  Pages 818 - 823

• DNA damage-dependent cyclin D1 proteolysis:  GSK3β holds the smoking gun

  Laura L. Pontano and J. Alan Diehl
  Pages 824 - 827

• Biological impact of mechanical stimuli on tumor metastasis

  David H. Craig and Marc D. Basson
  Pages 828 - 831

Reviews

• Cell “circadian” cycle: New role for mammalian core clock genes

  Laurence Borgs, Pierre Beukelaers, Renaud Vandenbosch, Shibeshih Belachew, Laurent Nguyen and Brigitte Malgrange
  Pages 832 - 837

• Tyrosine phosphorylation and CD95: A FAScinating switch

  Open Access Article

  Ignacio Sancho-Martinez and Ana Martin-Villalba
  Pages 838 - 842

• Let-7 and miR-200 microRNAs: Guardians against pluripotency and cancer progression

  Open Access Article

  Marcus E. Peter
  Pages 843 - 852

• Systemic siRNA delivery to leukocyte-implicated diseases

  Dan Peer and Motomu Shimaoka
  Pages 853 - 859

• Viral subversion of immunogenic cell death

  Oliver Kepp, Laura Senovilla, Lorenzo Galluzzi, Theocharis Panaretakis, Frederic Schlemmer, Frank Madeo, Laurence Zitvogel and Guido Kroemer
  Pages 860 - 869

Reports

• Systemic targeting of primary bone tumor and lung metastasis of high-grade osteosarcoma in nude mice with a tumor-selective strain of Salmonella typhymurium

  Katsuhiro Hayashi, Ming Zhao, Kensuke Yamauchi, Norio Yamamoto, Hiroyuki Tsuchiya, Katsuro Tomita, Hiroyuki Kishimoto, Michael Bouvet and Robert Hoffman
  Pages 870 - 875

• The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents

  Deborah R. Wysong, Arijit Chakravarty, Kara Hoar and Jeffrey A. Ecsedy
  Pages 876 - 888

• Nucleophosmin/B23 interacts with p21WAF1/CIP1 and contributes to its stability

  Jianyong Xiao, Zhiyi Zhang, George Gong Chen, Meifang Zhang, Yuanjie Ding, Jia Fu, Mingtao Li and Jing-Ping Yun
  Pages 889 - 895

• PTEN and p53 are required for hypoxia induced expression of maspin in glioblastoma cells

  Jacob A. Eitel, Khadijeh Bijangi-Vishehsaraei, M. Reza Saadatzadeh, Michael P. Murphy, Karen E. Pollok and Lindsey D. Mayo
  Pages 896 - 901

• Upregulation of Nox4 in the aging vasculature and its association with smooth muscle cell polyploidy

  Donald McCrann, Dan Yang, Hongjie Chen, Shannon Carroll and Katya Ravid
  Pages 902 - 908

• Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

  Irina N. Alimova, Bolin Liu, Zeying Fan, Susan M. Edgerton, Thomas Dillon, Stuart E. Lind and Ann D. Thor
  Pages 909 - 915

• The role of promoter CpG methylation in the epigenetic control of stem cell related genes during differentiation

  Temuujin Dansranjavin, Susanne Krehl, Thomas Mueller, Lutz P. Mueller, Hans-Joachim Schmoll and Reinhard H. Dammann
  Pages 916 - 924

• Human genome connectivity code links disease-associated SNPs, microRNAs and pyknons

  Gennadi V. Glinsky
  Pages 925 - 930

• A novel form of the telomere-associated protein TIN2 localizes to the nuclear matrix

  Patrick G. Kaminker, Sahn-Ho Kim, Pierre-Yves Desprez and Judith Campisi
  Pages 931 - 939

• CAML loss causes anaphase failure and chromosome missegregation

  Yu Liu, Liviu Malureanu, Karthik B. Jeganathan, David Dinh Tran, Lonn D. Lindquist, Jan M. van Deursen and Richard J. Bram
  Pages 940 - 949

Letters to the Editor

• Cell proliferation and migration are mutually exclusive cellular phenomena in vivo: Implications for cancer therapeutic strategies

  Ping-Pin Zheng, Lies-Anne Severijnen, Marcel van der Weiden, Rob Willemsen and Johan M. Kros
  Pages 950 - 951

• Auto-assembly as a new regulatory mechanism of noncoding RNA

  Florent Busi, Bastien Cayrol, Christophe Lavelle, Jacques LeDerout, Olivier Piétrement, Eric Le Cam, Frédéric Geinguenaud, Jérôme Lacoste, Philippe Régnier and Véronique Arluison
  Pages 952 - 954