Table of Contents

Volume 8, Issue 12

  June 15, 2009

  Pages 1813 - 1972

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Editorials: Cell Cycle Features

• TGFΒ versatility: PI3K as a critical mediator of distinct cell type and context specific responses

  Rod A. Rahimi and Edward B. Leof
  Pages 1813 - 1815

• An evolutionary conserved checkpoint controls abscission timing

  Patrick Steigemann and Daniel W. Gerlich
  Pages 1813 - 1815

• Second-end DNA capture in double-strand break repair: How to catch a DNA by its tail

  Open Access Article

  Amitabh V. Nimonkar and Stephen C. Kowalczykowski
  Pages 1816 - 1817

News & Views

• IDO recruits Tregs in melanoma

  Open Access Article

  George Prendergast, Richard Metz and Alexander J. Muller
  Pages 1818 - 1822

• NFκB inhibition and more: A side-by-side comparison of the inhibitors of IKK and proteasome

  Open Access Article

  Eugene S. Kandel
  Pages 1818 - 1822

• Histone acetylation floods the human cell cycle and DNA damage response

  Open Access Article

  Neda Delgoshaie, Hugo Wurtele and Alain Verreault
  Pages 1818 - 1822

• Forever young, slim and fit: Rapamycin to the rescue

  Open Access Article

  Zbigniew Darzynkiewicz
  Pages 1818 - 1822

• Sir2 and longevity: The p53 connection

  Open Access Article

  Johannes S. Bauer and Stephen L. Helfand
  Pages 1818 - 1822

• MicroRNAs: An important player in maintaining a balance between inflammation and tumor suppression

  Open Access Article

  Dipa Bhaumik, Christopher K. Patil and Judith Campisi
  Pages 1818 - 1822

Editor's Corner: In Their Own Words

• An interview with Dr. Frank Slack on his highly cited paper published in Cell Cycle

  Open Access Article

  
  Page 1823

Extra Views

• Regulation and function of yeast PAS kinase: A role in the maintenance of cellular integrity

  Julianne H. Grose, Eleanor Sundwall and Jared Rutter
  Pages 1824 - 1832

• MicroRNAs: Novel components in a muscle gene regulatory network

  Huating Wang, Hao Sun and Denis C. Guttridge
  Pages 1833 - 1837

• The WNT-5a derived peptide, Foxy-5, possesses dual properties that impair progression of ERα negative breast cancer

  Caroline E. Ford, Elin J. Ekström, Jillian Howlin and Tommy Andersson
  Pages 1838 - 1842

• DeubiKuitylation: A novel DUB enzymatic activity for the DNA repair protein, Ku70

  Moran Rathaus, Batya Lerrer and Haim Y. Cohen
  Pages 1843 - 1852

• The apoptotic ring: A novel entity with phosphorylated histones H2AX and H2B, and activated DNA damage response kinases

  Open Access Article

  Stéphanie Solier and Yves Pommier
  Pages 1853 - 1859

Perspectives

• Notch and Kras in pancreatic cancer: At the crossroads of mutation, differentiation and signaling

  Jean-Paul De La O and L. Charles Murtaugh
  Pages 1860 - 1864

• ATR kinase as master regulator of nucleotide excision repair during S phase of the cell cycle

  Yannick Auclair, Raphael Rouget and Elliot A. Drobetsky
  Pages 1865 - 1871

Reviews

• Targeting cancer-specific synthetic lethality in double-strand DNA break repair

  Benjamin J. Moeller, Renata Pasqualini and Wadih Arap
  Pages 1872 - 1876

• The pro-apoptotic action of stilbene-induced COX-2 in cancer cells: Convergence with the anti-apoptotic effect of thyroid hormone

  Hung-Yun Lin, Paul J. Davis, Heng-Yuan Tang, Shaker A. Mousa, Mary K. Luidens, Aleck H. Hercbergs and Faith B. Davis
  Pages 1877 - 1882

Spotlight

• Aging-suppressants: Cellular senescence (hyperactivation) and its pharmacologic deceleration

  Mikhail V. Blagosklonny
  Pages 1883 - 1887

Reports

• Rapamycin decelerates cellular senescence

  Zoya N. Demidenko, Svetlana G. Zubova, Elena I. Bukreeva, Valery A. Pospelov, Tatiana V. Pospelova and Mikhail V. Blagosklonny
  Pages 1888 - 1895

• Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence

  Zoya N. Demidenko, Michael Shtutman and Mikhail V. Blagosklonny
  Pages 1896 - 1900

• At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence

  Zoya N. Demidenko and Mikhail V. Blagosklonny
  Pages 1901 - 1904

• Crystallization of eIF4E complexed with eIF4GI peptide and glycerol reveals distinct structural differences around the cap-binding site

  Christopher J. Brown, Chandra S. Verma, Malcolm D. Walkinshaw and David P. Lane
  Pages 1905 - 1911

• Whi3 regulates morphogenesis in budding yeast by enhancing Cdk functions in apical growth

  Neus Colomina, Francisco Ferrezuelo, Emili Vergés, Martí Aldea and Eloi Garí
  Pages 1912 - 1920

• Aurora B kinase inhibition in mitosis: Strategies for optimizing the use of Aurora kinase inhibitors such as AT9283

  Jayne Curry, Hayley Angove, Lynsey Fazal, John Lyons, Matthias Reule, Neil Thompson and Nicola Wallis
  Pages 1921 - 1929

• Expression of indoleamine 2,3-dioxygenase in metastatic malignant melanoma recruits regulatory T cells to avoid immune detection and affects survival

  Jonathan R. Brody, Christina L. Costantino, Adam C. Berger, Takami Sato, Michael P. Lisanti, Charles J. Yeo, Robert V. Emmons and Agnieszka K. Witkiewicz
  Pages 1930 - 1934

• Heat-killed bacteria induce genome instability in mouse small intestine, liver and spleen tissues

  Igor Koturbash, James E. Thomas, Olga Kovalchuk and Igor Kovalchuk
  Pages 1935 - 1939

• Discovery of a novel proteasome inhibitor selective for cancer cells over non-transformed cells

  Aslamuzzaman Kazi, Harshani Lawrence, Wayne C. Guida, Mark L. McLaughlin, Gregory M. Springett, Norbert Berndt, Richard M. Yip and Said M. Sebti
  Pages 1940 - 1951

• Origin licensing and p53 status regulate Cdk2 activity during G1

  Open Access Article

  Kathleen R. Nevis, Marila Cordeiro-Stone and Jeanette Gowen Cook
  Pages 1952 - 1963

Letters to the Editor

• Role of E6/E7 onco-proteins of high-risk human papillomaviruses in human colorectal carcinogenesis

  Riccardo Ricciardi, Lina Ghabreau, Amber Yasmeen, Andrew D. Darnel, Nizar Akil and Ala-Eddin Al Moustafa
  Pages 1964 - 1965

• A novel mode of FoxM1 regulation: Positive auto-regulatory loop

  Marianna Halasi and Andrei Gartel
  Pages 1966 - 1967