Table of Contents

Volume 7, Issue 23

  December 1, 2008

  Pages 3617 - 3783

View covers archive

News

• Differential regulation of the PIKK kinase family by Tel2

  Open Access Article

  Simon J. Boulton
  Page 3617

Extra Views

• Working together and apart: The twisted relationship of the Mre11 complex and Chk2 in apoptosis and tumor suppression

  Travis H. Stracker and John H.J. Petrini
  Pages 3618 - 3621

• Stemness, cancer, and cancer stem cells

  Open Access Article

  David J. Wong, Eran Segal and Howard Y. Chang
  Pages 3622 - 3624

• Autophagy and T-cell education in the thymus: Eat yourself to know yourself

  Jelena Nedjic, Martin Aichinger and Ludger Klein
  Pages 3625 - 3628

• Cooperation of replication Protein A with the ubiquitin ligase Rad18 in DNA damage bypass

  Diana Huttner and Helle D. Ulrich
  Pages 3629 - 3633

Perspectives

• Regulation of lymphocyte fate by Ras/ERK signals

  Tomoharu Yasuda and Tomohiro Kurosaki
  Pages 3634 - 3640

• ARF in the mitochondria: The last frontier?

  Koji Itahana, Hilary V. Clegg and Yanping Zhang
  Pages 3641 - 3646

• Trim24 (Tif1α): An essential ‘brake’ for retinoic acid-induced transcription to prevent liver cancer

  Konstantin Khetchoumian, Marius Teletin, Johan Tisserand, Benjamin Herquel, Khalid Ouararhni and Régine Losson
  Pages 3647 - 3652

• DNA lesions and DNA damage response: Even long lasting relationships need a "break"

  Evi Soutoglou
  Pages 3653 - 3658

Reviews

• Early origin of cancer metastases: Dissemination and evolution of premalignant cells

  Stéphane Ansieau, George Hinkal, Clémence Thomas, Jérémy Bastid and Alain Puisieux
  Pages 3659 - 3663

• Role of the cyclin-dependent kinase 9-related pathway in mammalian gene expression and human diseases

  Gaetano Romano and Antonio Giordano
  Pages 3664 - 3668

• Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues

  Marcella Fulco and Vittorio Sartorelli
  Pages 3669 - 3679

Reports

• Disease phenocode analysis identifies SNP-guided microRNA maps (MirMaps) associated with human "master" disease genes

  Gennadi Glinsky
  Pages 3680 - 3694

• Mec1 function in the DNA damage response does not require its interaction with Tel2

  Open Access Article

  Carol M. Anderson and Elizabeth H. Blackburn
  Pages 3695 - 3698

• A mitotic role for GSK-3β kinase in Drosophila

  Open Access Article

  Edward J. Wojcik
  Pages 3699 - 3708

• Experimental testing of predicted myristoylation targets involved in asymmetric cell division and calcium-dependent signalling

  Open Access Article

  Wolfgang Benetka, Norbert Mehlmer, Sebastian Maurer-Stroh, Michaela Sammer, Manfred Koranda, Ralph Neumüller, Jörg Betschinger, Jürgen A. Knoblich, Markus Teige and Frank Eisenhaber
  Pages 3709 - 3719

• The fission yeast meiotic checkpoint kinase Mek1 regulates nuclear localization of Cdc25 by phosphorylation

  Open Access Article

  Livia Pérez-Hidalgo, Sergio Moreno and Pedro A. San-Segundo
  Pages 3720 - 3730

• DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation

  Jan Tamminga, Palak Kathiria, Igor Koturbash and Olga Kovalchuk
  Pages 3731 - 3736

• Differential post-transcriptional regulation of two Ink4 proteins, p18Ink4c and p19Ink4d

  Open Access Article

  Antoine Forget, Olivier Ayrault, Willem den Besten, Mei-Ling Kuo, Charles J. Sherr and Martine F. Roussel
  Pages 3737 - 3746

• Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2

  Xiao-Feng Le, Weiqun Mao, Chunhua Lu, Angela Thornton, John V. Heymach, Anil K. Sood and Robert C. Bast Jr.
  Pages 3747 - 3758

• Hexamethylene Bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF-κB activity: Implications for cancer therapy

  Open Access Article

  Anwesha Dey, Eetsin Wong, Nelly Kua, Hsiang Ling Teo, Vinay Tergaonkar and David Lane
  Pages 3759 - 3767

• Differential regulation of cyclin D1 and D2 in protecting against cardiomyocyte proliferation

  Open Access Article

  Mimi Tamamori-Adachi, Ikuko Goto, Kazuhiko Yamada and Shigetaka Kitajima
  Pages 3768 - 3774

• E2F3 plays an essential role in cardiac development and function

  Jennifer C. King, Ivan P. G. Moskowitz, Patrick G. Burgon, Ferhaan Ahmad, James R. Stone, Jonathan G. Seidman and Jacqueline A. Lees
  Pages 3775 - 3780

Letter to the Editor

• BRCA1 mutations contribute to cell motility and invasion by affecting its main regulators

  Amber Yasmeen, Wenchao Liu, Hafedh Dekhil, Amal Kassab, Raquel Aloyz, William D. Foulkes and Ala-Eddin Al Moustafa
  Pages 3781 - 3783