Table of Contents

Volume 7, Issue 2

  January 15, 2008

  Pages 127 - 271

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• Ras nanoclusters: Combining digital and analog signaling

  Angus Harding and John F. Hancock
  Pages 127 - 134

• Niche players: Spermatogonial progenitors marked by GPR125

  Marco Seandel, Ilaria Falciatori, Sergey V. Shmelkov, Jiyeon Kim, Daylon James and Shahin Rafii
  Pages 135 - 140

• Mechanisms of mammalian polo-like kinase 1 (Plk1) localization: Self- versus non-self-priming

  Kyung S. Lee, Jung-Eun Park, Young Hwi Kang, Wendy Zimmerman, Nak-Kyun Soung, Yeon-Sun Seong, Sahng-June Kwak and Raymond L. Erikson
  Pages 141 - 145

• Control of the Cdc6 replication licensing factor in metazoa: the role of nuclear export and the CUL4 ubiquitin ligase

  Jihyun Kim and Edward T. Kipreos
  Pages 146 - 150

• What makes centromeric cohesion resistant to separase cleavage during meiosis I but not during meiosis II?

  Juraj Gregan, Cornelia Rumpf, Zhang Li and Lubos Cipak
  Pages 151 - 153

Perspectives

• p53 promoter selection: choosing between life and death

  Sanjeev Das, Sarah A. Boswell, Stuart A. Aaronson and Sam W. Lee
  Pages 154 - 157

• The common germline Arg72Pro polymorphism of p53 and increased longevity in humans

  Open Access Article

  Stig E. Bojesen and Børge G. Nordestgaard
  Pages 158 - 163

• The Wip1 phosphatase and Mdm2: Cracking the “Wip” on p53 stability

  Xiongbin Lu, Thuy-Ai Nguyen, Xinna Zhang and Lawrence A. Donehower
  Pages 164 - 168

• MAP kinase p38 and its relation to T cell anergy and suppressor function of regulatory T cells

  Henric S. Adler and Kerstin Steinbrink
  Pages 169 - 175

• Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells

  Massimo Olivotto and Persio Dello Sbarba
  Pages 176 - 187

• Metastatic cancer stem cells: A new target for anti-cancer therapy?

  Patrick C. Hermann, Stephan L. Huber and Christopher Heeschen
  Pages 188 - 193

• TNF signaling gets FLIPped off: TNF-induced regulation of FLIP

  Stuart A. Rushworth, Alison Taylor, Susana Langa and David J. MacEwan
  Pages 194 - 199

Review

• Genetic Similarities Between Organogenesis and Tumorigenesis of the Lung

  Scott Powers and David Mu
  Pages 200 - 204

Priority Report

• Specific isoforms of p73 control the induction of cell death induced by the viral proteins, E1A or Apoptin

  Poramaporn Klanrit, Marcella B. Flinterman, Edward W. Odell, Gennaro Melino, Richard Killick, James S. Norris and Mahvash Tavassoli
  Pages 205 - 215

Reports

• Basal c-Jun N-terminal kinases promote mitotic progression through histone H3 phosphorylation

  Kyunghee Lee and Kiwon Song
  Pages 216 - 221

• Specific inhibition of Mdm2-mediated neddylation by Tip60

  Christoph Dohmesen, Max Koeppel and Matthias Dobbelstein
  Pages 222 - 231

• Synergystic induction of HIF-1α transcriptional activity by hypoxia and lipopolysaccharide in macrophages

  Zenghui Mi, Annamaria Rapisarda, Lynn Taylor, Alan Brooks, Mark Creighton-Gutteridge, Giovanni Melillo and Luigi Varesio
  Pages 232 - 241

• Functional analyses of the cancer stem cell-like properties of human endometrial tumor initiating cells

  Open Access Article

  Anne M. Friel, Petra A. Sergent, Christine Patnaude, Paul P. Szotek, Esther Oliva, David T. Scadden, Michael V. Seiden, Rosemary Foster and Bo R. Rueda
  Pages 242 - 249

• A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature

  Jeffrey D. Hancock and Stephen L. Lessnick
  Pages 250 - 256

• PI3K/Akt/FOXO3a pathway contributes to thrombopoietin-induced proliferation of primary megakaryocytes in vitro and in vivo via modulation of p27Kip1

  Takafumi Nakao, Amy E. Geddis, Norma E. Fox and Kenneth Kaushansky
  Pages 257 - 266

Letters to the Editor

• A new mitotic-cell specific monoclonal antibody

  Martine Cazales, Muriel Quaranta, Valérie Lobjois, Denis Jullien, Talal Al Saati, Georges Delsol and Bernard Ducommun
  Pages 267 - 268

• HSV-1 UL45 encodes a carbohydrate binding C-type lectin protein

  Lucjan S. Wyrwicz, Krzysztof Ginalski and Leszek Rychlewski
  Pages 269 - 271