Table of Contents

Volume 7, Issue 18

  September 15, 2008

  Pages 2779 - 2943

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News

• Sentinels of DNA integrity in stem cells: Safeguarding future generations of cells

  Open Access Article

  Janet L. Paluh
  Pages 2779 - 2780

• Protein kinases coordinately regulate the p53:ΔNp63α axis after DNA damage

  Open Access Article

  Lisa Y. Pang and Ted R. Hupp
  Pages 2779 - 2780

Extra Views

• p57^kip2's role beyond Schwann cell cycle control

  André Heinen, David Kremer, Hans-Peter Hartung and Patrick Küry
  Pages 2781 - 2786

• The role of glypican-3 in the regulation of body size and cancer

  Jorge Filmus and Mariana Capurro
  Pages 2787 - 2790

• Translational control and cancer therapy

  Konstantinos J. Mavrakis and Hans-Guido Wendel
  Pages 2791 - 2794

• The yin and yang of the Cdkn2a locus in senescence and aging

  Darren J. Baker, Fang Jin and Jan M. van Deursen
  Pages 2795 - 2802

• Regulation of innate immunity by inositol 1,3,4,5-tetrakisphosphate

  Yonghui Jia, Stephane Schurmans and Hongbo R. Luo
  Pages 2803 - 2808

• Activation of ATR and related PIKKs

  Daniel A. Mordes and David Cortez
  Pages 2809 - 2812

• GSK-3b inhibition: At the crossroad between Akt and mTOR constitutive activation to enhance cyclin D1 protein stability in mantle cell lymphoma

  Jessica Dal Col and Riccardo Dolcetti
  Pages 2813 - 2816

• Akt regulation and lung cancer: A novel role and mechanism of action for the tumor suppressor Par-4

  Maria T. Diaz-Meco and Jorge Moscat
  Pages 2817 - 2820

Perspectives

• Sirt1, Notch and stem cell "age asymmetry"

  Charlie R. Mantel, Rui-Hong Wang, Chuxia Deng and Hal E. Broxmeyer
  Pages 2821 - 2825

• Emerging functions of c-kit and its ligand stem cell factor in dendritic cells

  Prabir Ray, Nandini Krishnamoorthy and Anuradha Ray
  Pages 2826 - 2832

• What drives intense apoptosis resistance and propensity for necrosis in glioblastoma? A role for Bcl2L12 as a multifunctional cell death regulator

  Alexander H. Stegh, Lynda Chin, David N. Louis and Ronald A. DePinho
  Pages 2833 - 2839

Review

• The long and short of inverted repeat genes in animals: MicroRNAs, mirtrons and hairpin RNAs

  Katsutomo Okamura, Wei-Jen Chung and Eric C. Lai
  Pages 2840 - 2845

Reports

• ATM kinase is a master switch for the ΔNp63α phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage

  Yiping Huang, Tanusree Sen, Jatin Nagpal, Sunil Upadhyay, Barry Trink, Edward Ratovitski and David Sidransky
  Pages 2846 - 2855

• Regulation of Sp1 by cell cycle related proteins

  Alicia Tapias, Carlos J. Ciudad, Igor B. Roninson and Véronique Noé
  Pages 2856 - 2867

• Focal adhesion components are essential for mammalian cell cytokinesis

  Sasha H. Shafikhani, Keith Mostov and Joanne Engel
  Pages 2868 - 2876

• Phosphoinositide 3-kinase signaling overrides a G₂ phase arrest checkpoint and promotes aberrant cell cycling and death of hematopoietic cells after DNA damage

  Dipali Nimbalkar and Frederick W. Quelle
  Pages 2877 - 2885

• Chmp1A functions as a novel tumor suppressor gene in human embryonic kidney and ductal pancreatic tumor cells

  Open Access Article

  Jing Li, Natalia Belogortseva, David Porter and Maiyon Park
  Pages 2886 - 2893

• Knockdown of B-Raf impairs spindle formation and the mitotic checkpoint in human somatic cells

  Meghan Borysova, Yongping Cui, Madeline Snyder and Thomas Guadagno
  Pages 2894 - 2901

• DNA repair by nonhomologous end joining and homologous recombination during cell cycle in human cells

  Zhiyong Mao, Michael Bozzella, Andrei Seluanov and Vera Gorbunova
  Pages 2902 - 2906

• The fold recognition of CP2 transcription factors gives new insights into the function and evolution of tumor suppressor protein p53

  Katarzyna Kokoszyńska, Jerzy Ostrowski, Leszek Rychlewski and Lucjan S. Wyrwicz
  Pages 2907 - 2915

• Color-coded imaging of splenocyte-pancreatic cancer cell interactions in the tumor microenvironment

  Michele McElroy, Sharmeela Kaushal, Michael Bouvet and Robert M. Hoffman
  Pages 2916 - 2921

• Activation of DNA damage response signaling in mouse embryonic stem cells

  Ilya A. Chuykin, Maria S. Lianguzova, Tatiana V. Pospelova and Valery A. Pospelov
  Pages 2922 - 2928

• Efficient differentiation of hESCs into endothelial cells in vitro is secured by epigenetic changes

  Maria A. Lagarkova, Pavel Y. Volchkov, Elena S. Philonenko and Sergei L. Kiselev
  Pages 2929 - 2935

• Targeting Hsp90 prevents escape of breast cancer cells from tyrosine kinase inhibition

  Itai Pashtan, Shinji Tsutsumi, Suiquan Wang, Wanping Xu and Len Neckers
  Pages 2936 - 2941