Table of Contents
Volume 7, Issue 16
August 15, 2008
Pages 2451 - 2608
News
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Remarkable features of tiny RNA molecules: Highlights of revolutionary discoveries on the path from the bench to bedside
Open Access Article
Gennadi V. Glinsky
Page 2451
Extra Views
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Modulation of the "blood-tumor" barrier improves immunotherapy
Mitali Manzur, Juliana Hamzah and Ruth Ganss
Pages 2452 - 2455
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Strap: A versatile transcription co-factor
Danmei Xu and Nicholas B La Thangue
Pages 2456 - 2457
Perspectives
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microRNA(interference) networks are embedded in the gene regulatory networks
Letizia Pitto, Andrea Ripoli, Federico Cremisi and Giuseppe Rainaldi
Pages 2458 - 2461
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Mechanotransduction and anoikis: Death and the homeless cell
Zhenyi Ma, Zhe Liu, David P. Myers and Lance S. Terada
Pages 2462 - 2465
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Targeting the eIF4F translation initiation complex for cancer therapy
Bruce W. Konicek, Chad A. Dumstorf and Jeremy R. Graff
Pages 2466 - 2471
Reviews
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RecQ family helicases in genome stability: Lessons from gene disruption studies in DT40 cells
Open Access Article
Masayuki Seki, Makoto Otsuki, Yutaka Ishii, Shusuke Tada and Takemi Enomoto
Pages 2472 - 2478
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Cell death specification in C. elegans
Erin Peden, Darrell J. Killian and Ding Xue
Pages 2479 - 2484
Spotlight on microRNA
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MicroRNAs and cancer: An overview
Pedro P. Medina and Frank J. Slack
Pages 2485 - 2492
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Functional integration of microRNAs into oncogenic and tumor suppressor pathways
Craig D. Lotterman, Oliver A. Kent and Joshua T. Mendell
Pages 2493 - 2499
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Lessons from microRNA mutants in worms, flies and mice
Peter Smibert and Eric C. Lai
Pages 2500 - 2508
Reports
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Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism
Ayanna S. Augustus, Jonathan Buchanan, Ellen Gutman, Giuseppe Rengo, Richard G. Pestell, Paolo Fortina, Walter J. Koch, Andre Bensadoun, E. Dale Abel and Michael P. Lisanti
Pages 2509 - 2518
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p53-Ubl fusions as models of ubiquitination, sumoylation and neddylation of p53
Open Access Article
Stephanie Carter and Karen H. Vousden
Pages 2519 - 2528
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A role for Drosophila Polo protein in chromosome resolution and segregation during mitosis
Susana Godinho and Álvaro A. Tavares
Pages 2529 - 2534
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p53 binding to the p21 promoter is dependent on the nature of DNA damage
Ewelina Bodzak, Michael D. Blough, Patrick W.K. Lee and Richard Hill
Pages 2535 - 2543
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GFP reporter mice for the retinoblastoma-related cell cycle regulator p107
Open Access Article
Deborah L. Burkhart, Patrick Viatour, Victoria M. Ho and Julien Sage
Pages 2544 - 2552
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Autocrine regulation of glioblastoma cell-cycle progression, viability and radioresistance through the VEGF-VEGFR2 (KDR) interplay
Petra Knizetova, Jiri Ehrmann, Alice Hlobilkova, Iveta Vancova, Ondrej Kalita, Zdenek Kolar and Jiri Bartek
Pages 2553 - 2561
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Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex
Pradeep S. Pallan and Martin Egli
Pages 2562 - 2569
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An SNP-guided microRNA map of fifteen common human disorders identifies a consensus disease phenocode aiming at principal components of the nuclear import pathway
Open Access Article
Gennadi V. Glinsky
Pages 2570 - 2583
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Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model
Gustavo Palacios, Howard C. Crawford, Angelina Vaseva and Ute M. Moll
Pages 2584 - 2590
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Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
Open Access Article
Dmitri Lodygin, Valery Tarasov, Alexey Epanchintsev, Carola Berking, Tatjana Knyazeva, Henrike Körner, Piotr Knyazev, Joachim Diebold and Heiko Hermeking
Pages 2591 - 2600
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Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs
Susana Gonzalez, David G. Pisano and Manuel Serrano
Pages 2601 - 2608