Table of Contents

Volume 7, Issue 11

  June 1, 2008

  Pages 1503 - 1692

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Opinions and Viewpoints

• Embryotic evolution: An ancient question, a new answer

  Open Access Article

  Christian Schwabe
  Pages 1503 - 1506

Extra Views

• Cep192 and the generation of the mitotic spindle

  Maria Ana Gomez-Ferreria and David J. Sharp
  Pages 1507 - 1510

• (Un)expected roles of c-IAPs in apoptotic and NFκB signaling pathways

  Eugene Varfolomeev and Domagoj Vucic
  Pages 1511 - 1521

• USP22, an hSAGA subunit and potential cancer stem cell marker, reverses the polycomb-catalyzed ubiquitylation of histone H2A

  Xiao-yong Zhang, Harla Pfeiffer, Alan Thorne and Steven B. McMahon
  Pages 1522 - 1524

• TRAIL death receptors as tumor suppressors and drug targets

  Open Access Article

  Niklas Finnberg and Wafik S. El-Deiry
  Pages 1525 - 1528

• Cancerous miRNAs and their regulation

  Xu-Bao Shi, Clifford G. Tepper and Ralph W. deVere White
  Pages 1529 - 1538

• Promoter-proximal Pol II: When stalling speeds things up

  Sergei Nechaev and Karen Adelman
  Pages 1539 - 1544

• Cell cycle control of microRNA-mediated translation regulation

  Shobha Vasudevan, Yingchun Tong and Joan A. Steitz
  Pages 1545 - 1549

• Sin3B: An essential regulator of chromatin modifications at E2F target promoters during cell cycle withdrawal

  Kathryn B. Grandinetti and Gregory David
  Pages 1550 - 1554

• Checkpoints meet the transcription at a novel histone milestone (H3-T11)

  Midori Shimada and Makoto Nakanishi
  Pages 1555 - 1559

Perspectives

• Understanding how kinase-targeted therapies work

  Sabrina Arena and Alberto Bardelli
  Pages 1560 - 1563

• Extracellular HSP90: Conquering the cell surface

  Katerina Sidera and Evangelia Patsavoudi
  Pages 1564 - 1568

• Interfering with protein-protein interactions: Potential for cancer therapy

  Tomoyuki Tanaka and Terence H. Rabbitts
  Pages 1569 - 1574

Inferences and Hypotheses

• Does the absence of ABCC6 (Multidrug Resistance Protein 6) in patients with Pseudoxanthoma elasticum prevent the liver from providing sufficient vitamin K to the periphery?

  Open Access Article

  Piet Borst, Koen van de Wetering and Reinier Schlingemann
  Pages 1575 - 1579

Brief Report

• Identification and characterization of a novel Mdm2 splice variant acutely induced by the chemotherapeutic agents Adriamycin and Actinomycin D

  Nathan H. Lents, Leroy W. Wheeler, Joseph J. Baldassare and Brian David Dynlacht
  Pages 1580 - 1586

Reports

• Involvement of N-terminally truncated variants of p73, ΔTAp73, in head and neck squamous cell cancer: A comparison with p53 mutations

  Laetitia Faridoni-Laurens, Sophie Tourpin, Samar Alsafadi, Michel Barrois, Stephane Temam, François Janot, Serge Koscielny, Jacques Bosq, Jean Bénard and Jean-Charles Ahomadegbe
  Pages 1587 - 1596

• Functional independency between catalytic activity and subcellular targeting of Polo-like kinase-1: Phenotypes of ectopic overexpression of various mutants

  Jae-Hoon Ji and Young-Joo Jang
  Pages 1597 - 1603

• Elevated MDM2 boosts the apoptotic activity of p53-MDM2 binding inhibitors by facilitating MDMX degradation

  Mingxuan Xia, Dejan Knezevic, Christian Tovar, Baoying Huang, David C. Heimbrook and Lyubomir T. Vassilev
  Pages 1604 - 1612

• Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes

  Yiping Huang, Mohammad Obaidul Hoque, Feng Wu, Barry Trink, David Sidransky and Edward A. Ratovitski
  Pages 1613 - 1622

• Genetic stability of senescence reverted cells: Genome reduction division of polyploidy cells, aneuploidy and neoplasia

  Kirsten H. Walen
  Pages 1623 - 1629

• Phenotype-defining functions of multiple non-coding RNA pathways

  Open Access Article

  Gennadi V. Glinsky
  Pages 1630 - 1639

• ARC (apoptosis repressor with caspase recruitment domain) is a novel marker of human colon cancer

  Isabelle Mercier, Magalis Vuolo, Jean-Francois Jasmin, Christina M. Medina, Mark Williams, John M. Mariadason, Hong Qian, Xiaonan Xue, Richard G. Pestell, Michael P. Lisanti and Richard N. Kitsis
  Pages 1640 - 1647

• Selective cytotoxicity of synthesized procyanidin 3-O-Galloylepicatechin-4b,8-3-O-galloylcatechin to human cancer cells

  Min Kim, Xiaofang Wu, Insun Song, Maofu Fu, Seo-Hee Chang, Michael P. Lisanti and Richard G. Pestell
  Pages 1648 - 1657

• Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice

  Igor Koturbash, Franz J. Zemp, Kristy Kutanzi, Lidiya Luzhna, Jonathan Loree, Bryan Kolb and Olga Kovalchuk
  Pages 1658 - 1667

• DNA damage-induced S phase arrest in human breast cancer depends on Chk1, but G₂ arrest can occur independently of Chk1, Chk2 or MAPKAPK2

  Wen-Hui Zhang, Alissa Poh, Andrew A. Fanous and Alan Eastman
  Pages 1668 - 1677

• A global genomic view of MIF knockdown-mediated cell cycle arrest

  Lingfeng Liu, Chaoneng Ji, Jinzhong Chen, Yao Li, Xuping Fu, Yi Xie, Shaohua Gu and Yumin Mao
  Pages 1678 - 1692