Table of Contents

Volume 6, Issue 1

  January 1, 2007

  Pages 3 - 110

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• Phosphatase and Feedback Regulation of Raf-1 Signaling

  Amardeep S. Dhillon, Alex von Kriegsheim, Joan Grindlay and Walter Kolch
  Pages 3 - 7

• Oct-3/4: Not Just a Gatekeeper of Pluripotency for Embryonic Stem Cell, a Cell Fate Instructor through a Gene Dosage Effect

  Sonia Stefanovic and Michel Pucéat
  Pages 8 - 10

• Is Ribosome Synthesis Controlled by Pol I Transcription?

  Open Access Article

  Stéphane Chédin, Arnaud Laferté, Tran Hoang, Denis LAFONTAINE, Michel Riva and Christophe Carles
  Pages 11 - 15

• An Emerging Role for Ca2+/Calcineurin/NFAT Signaling in Cancerogenesis

  Malte Buchholz and Volker Ellenrieder
  Pages 16 - 19

• S6-Haploinsufficiency Activates the p53 Tumor Suppressor

  Linda Panić, Jacques Montagne, Maja Cokarić and Siniša Volarević
  Pages 20 - 24

• TOR-in(g) the Nucleus

  Chi Kwan Tsang and X.F. Steven Zheng
  Pages 25 - 29

• A Mechanosensory System Controls Cell Shape Changes During Mitosis

  Janet C. Effler, Pablo A. Iglesias and Douglas N. Robinson
  Pages 30 - 35

• Involvement of Cellular Membrane Traffic Proteins in Poliovirus Replication

  Open Access Article

  George A. Belov and Ellie Ehrenfeld
  Pages 36 - 38

• Bilirubin and Biliverdin Treatment of Atherosclerotic Diseases

  R. Öllinger, K. Yamashita, Martin Bilban, A. Erat, P. Kogler, M. Thomas, E. Csizmadia, A. Usheva, R. Margreiter and Fritz H. Bach
  Pages 39 - 43

Perspectives

• Polyclonal Tumors in the Mammalian Intestine: Are Interactions Among Multiple Initiated Clones Necessary for Tumor Initiation, Growth, and Progression?

  Richard B. Halberg and William F. Dove
  Pages 44 - 51

• Tumor Suppressor Dosage Regulates Stem Cell Dynamics during Aging

  Catherine Gatza, Lynette Moore, Melissa Dumble and Lawrence A. Donehower
  Pages 52 - 55

• The Role of VHL in the Regulation of E-Cadherin: A New Connection in an Old Pathway

  Ryan C. Russell and Michael Ohh
  Pages 56 - 59

• Cysteine Cathepsins and the Cutting Edge of Cancer Invasion

  Open Access Article

  Vasilena Gocheva and Johanna A. Joyce
  Pages 60 - 64

• Controlling Gene Expression through RNA Regulons: The Role of the Eukaryotic Translation Initiation Factor eIF4E

  Open Access Article

  Biljana Culjkovic, Ivan Topisirovic and Katherine L.B. Borden
  Pages 65 - 69

Analytical Review

• Mitotic Arrest and Cell Fate: Why and How Mitotic Inhibition of Transcription Drives Mutually Exclusive Events

  Mikhail V. Blagosklonny
  Pages 70 - 74

Brief Reports

• The Nuclear Envelope and Spindle Pole Body-Associated Mps3 Protein Bind Telomere Regulators and Function in Telomere Clustering

  Lisa M. Antoniacci, Margaret Kenna and Robert V. Skibbens
  Pages 75 - 79

• CBF-1 (RBP-Jk) Binds to the PTEN Promoter and Regulates PTEN Gene Expression

  Jarrett T. Whelan, Siiri L. Forbes and Fred E. Bertrand
  Pages 80 - 84

Analytical Report

• Exploring Mechanisms of the DNA-Damage Response: p53 Pulses and their Possible Relevance to Apoptosis

  Open Access Article

  Tongli Zhang, Paul Brazhnik and John J. Tyson
  Pages 85 - 94

Reports

• CYFIP2, a Direct p53 Target, is Leptomycin-B Sensitive

  Roger S. Jackson II, Yong-Jig Cho, Susanne Stein and Peng Liang
  Pages 95 - 103

• Pharmacological Abrogation of S-Phase Checkpoint Enhances the Anti-Tumor Activity of Gemcitabine In Vivo

  Open Access Article

  David J. Matthews, Michael Yakes, Jason Chen, Michele Tadano, Lester Bornheim, Douglas O. Clary, Albert Tai, Jill M. Wagner, Nicole Miller, Yong D. Kim, Scott Robertson, Louis Murray and Larry M. Karnitz
  Pages 104 - 110