Table of Contents

Volume 5, Issue 15

  August 1, 2006

  Pages 1587 - 1729

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• Systematic Proteome and Transcriptome Analysis of Stem Cell Populations

  Richard D. Unwin, Anthony D. Whetton
  Pages 1587 - 1591

• CtIP, a Multivalent Adaptor Connecting Transcriptional Regulation, Checkpoint Control and Tumor Suppression

  Guikai Wu and Wen-Hwa Lee‡
  Pages 1592 - 1596

Perspectives

• Stromal Fibroblasts in Cancer: A Novel Tumor-Promoting Cell Type

  Akira Orimo and Robert A. Weinberg
  Pages 1597 - 1601

• Is There A Pre-RC Checkpoint That Cancer Cells Lack?

  Eric Lau and Wei Jiang
  Pages 1602 - 1606

• Germline Mutations in Components of the Ras Signaling Pathway in Noonan Syndrome and Related Disorders

  Christian P. Kratz, Suzanne Schubbert, Gideon Bollag, Charlotte M. Niemeyer, Kevin M. Shannon and Martin Zenker
  Pages 1607 - 1611

• Hedgehog Signal Transduction: Signal Integration and Cross Talk in Development and Cancer

  Natalia A. Riobo, Ke Lu and Charles P. Emerson, Jr
  Pages 1612 - 1615

Reviews

• Restricting Apoptosis for Postmitotic Cell Survival and its Relevance to Cancer

  Kevin M. Wright and Mohanish Deshmukh
  Pages 1616 - 1620

• Targeting c-Myc, Ras and IGF Cascade to Treat Cancer and Vascular Disorders

  Filomena de Nigris, Maria Luisa Balestrieri and Claudio Napoli
  Pages 1621 - 1628

Brief Report

• Oxidative Changes in the DNA of Stroma and Epithelium from the Female Breast: Potential Implications for Breast Cancer

  Donald C. Malins, Katie M. Anderson, Pawel Jaruga, Callie R. Ramsey, Naomi K. Gilman, Virginia M. Green, Steven W. Rostad, Joanne T. Emerman and Miral Dizdaroglu
  Pages 1629 - 1632

Reports

• Disrupting the Entry Barrier and Attacking Brain Tumors: The Role of the Neisseria Lipobox-Containing H.8 Epitope and the Laz Protein

  Chang Soo Hong, Tohru Yamada, Arsenio M. Fialho, Tapas K. Das Gupta and Ananda M. Chakrabarty
  Pages 1633 - 1641

• Azurin, Plasmodium falciparum Malaria and HIV/AIDS: Inhibition of Parasitic and Viral Growth by Azurin

  Anita Chaudhari, Arsenio M. Fialho, Deena Ratner, Phalguni Gupta, Chang Soo Hong, Soumen Kahali, Tohru Yamada, Kasturi Haldar, Wonhwa Cho, Virander S. Chauhan, Tapas K. Das Gupta and Ananda M. Chakrabarty
  Pages 1642 - 1648

• CDC25B Phosphorylation by p38 and MK-2

  Mathieu Lemaire, Carine Froment, Rose Boutros, Odile Mondesert, Angel R. Nebreda, Bernard Monsarrat and Bernard Ducommun
  Pages 1649 - 1653

• Anti-HER2 Antibody Trastuzumab Inhibits CDK2-Mediated NPAT and Histone H4 Expression via PI3K Pathway

  Xiao-Feng Le, Isabelle Betrosian, Weiqun Mao, Mollianne Murray, Zhen Lu, Khandan Keyomarsi, Mong-Hong Lee, Jiyong Zhao and Robert C. Bast, Jr.
  Pages 1654 - 1661

• Activation of Mitochondrial Pathway is Crucial for Tumor Selective Induction of Apoptosis by LAQ824

  Shaowen Wang, Yan Yan-Neale, Richard Cai, Irina Alimov and Dalia Cohen
  Pages 1662 - 1668

• Nitrogen Oxide-Releasing Aspirin Induces Histone H2AX Phosphorylation, ATM Activation and Apoptosis Preferentially in S-Phase Cells: Involvement of Reactive Oxygen Species

  Toshiki Tanaka, Akira Kurose, H. Dorota Halicka, Xuan Huang, Frank Traganos and Zbigniew Darzynkiewicz
  Pages 1669 - 1674

• L2DTL/CDT2 Interacts with the CUL4/DDB1 Complex and PCNA and Regulates CDT1 Proteolysis in Response to DNA Damage

  Open Access Article

  Leigh Ann Higa, Damon Banks, Min Wu, Ryuji Kobayashi, Hong Sun and Hui Zhang
  Pages 1675 - 1680

• The Bloom Syndrome Helicase is a Substrate of the Mitotic Cdc2 Kinase

  Emilie Bayart, Stéphanie Dutertre, Christian Jaulin, Rong-Bing Guo, Xu Guang Xi and Mounira Amor-Guéret
  Pages 1681 - 1686

• Cyclin B Dissociation from CDK1 Precedes its Degradation Upon MPF Inactivation in Mitotic Extracts of Xenopus laevis Embryos

  Franck Chesnel, Franck Bazile, Aude Pascal and Jacek Z. Kubiak
  Pages 1687 - 1698

• Reverse Mutational Analysis Reveals Threonine-373 as a Potentially Sufficient Phosphorylation Site for Inactivation of the Retinoblastoma Tumor Suppressor Protein (pRB)

  Nathan H. Lents, Laura L. Gorges and Joseph J. Baldassare
  Pages 1699 - 1707

• Cdk1/Cyclin B-Mediated Phosphorylation Stabilizes SREBP1 During Mitosis

  Open Access Article

  Maria T. Bengoechea-Alonso and Johan Ericsson
  Pages 1708 - 1718

• L2DTL/CDT2 and PCNA Interact with p53 and Regulate p53 Polyubiquitination and Protein Stability through MDM2 and CUL4A/DDB1 Complexes

  Open Access Article

  Damon Banks, Min Wu, Leigh Ann Higa, Nadia Gavrilova, Junmin Quan, Tao Ye, Ryuji Kobayashi, Hong Sun and Hui Zhang
  Pages 1719 - 1729