Table of Contents

Volume 5, Issue 14

  July 15, 2006

  Pages 1477 - 1582

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• New Directions for Neurodegenerative Disease Therapy: Using Chemical Compounds to Boost the Formation of Mutant Protein Inclusions

  Open Access Article

  Ruth A. Bodner, David E. Housman and Aleksey G. Kazantsev
  Pages 1477 - 1480

• BRCA1-Mediated Ubiquitylation

  Simon J. Boulton
  Pages 1481 - 1486

• APC/C-Mediated Degradation in Early Mitosis: How to Avoid Spindle Assembly Checkpoint Inhibition

  Open Access Article

  Andrew M. Fry and Hiroyuki Yamano
  Pages 1487 - 1491

• A Novel Link Between SUMO Modification and Cancer Metastasis

  Sung Hee Baek
  Pages 1492 - 1495

• The Double Life of UPF1 in RNA and DNA Stability Pathways

  Claus M. Azzalin and Joachim Lingner
  Pages 1496 - 1498

• Partitioning Viral Genomes in Mitosis: Same Idea, Different Targets

  Open Access Article

  Alison A. McBride, Jaquelline G. Oliveira and Maria G. McPhillips
  Pages 1499 - 1502

Perspectives

• Transcriptional Regulation by the Proteasome as a Mechanism for Cellular Protein

  Kathryn L. Auld and Pamela A. Silver
  Pages 1503 - 1505

• Novel Functions for Cell Cycle Genes in Nervous System Development

  Kelly A. McClellan and Ruth S. Slack
  Pages 1506 - 1513

• ERK and Beyond: Insights from B-Raf and Raf-1 Conditional Knockouts

  Gergana Galabova-Kovacs, Andrea Kolbus, Dana Matzen, Katrin Meiss, Daniela Piazzolla, Cristina Rubiolo, Katharina Steinitz and Manuela Baccarini
  Pages 1514 - 1518

• Deciphering the Mammary Epithelial Cell Hierarchy

  John Stingl, Afshin Raouf, Peter Eirew and Connie J. Eaves
  Pages 1519 - 1522

• Regulation of PTEN Function as a PIP3 Gatekeeper Through Membrane Interaction

  Francisca Vazquez and Peter Devreotes
  Pages 1523 - 1527

• Differentiation of Neuronal Cells in Fragile X Syndrome

  Maija Castrén
  Pages 1528 - 1530

Review

• Unique Conditionally Replication Competent Bipartite Adenoviruses—Cancer Terminator Viruses (CTV): Efficacious Reagents for Cancer Gene Therapy

  Devanand Sarkar, Zao-zhong Su and Paul B. Fisher
  Pages 1531 - 1536

Reports

• A Two-Hit Mechanism for Pre-Mitotic Arrest of Cancer Cell Proliferation by a Polyamide-Alkylator Conjugate

  David Alvarez, C. James Chou, Lucia Latella, Samantha G. Zeitlin, Sherman Ku, Pier Lorenzo Puri, Peter B. Dervan and Joel M. Gottesfeld
  Pages 1537 - 1548

• Budding Yeast Sae2 is an In Vivo Target of the Mec1 and Tel1 Checkpoint Kinases During Meiosis

  Hugo Cartagena-Lirola, Ilaria Guerini, Valeria Viscardi, Giovanna Lucchini and Maria Pia Longhese
  Pages 1549 - 1559

• The Receptor Tyrosine Kinase Met and Its Ligand Hepatocyte Growth Factor are Clustered at Excitatory Synapses and Can Enhance Clustering of Synaptic Proteins

  Open Access Article

  Stephanie J. Tyndall and Randall S. Walikonis
  Pages 1560 - 1568

• Overexpression of the Anaphase Promoting Complex/Cyclosome Inhibitor Emi1 Leads to Tetraploidy and Genomic Instability of p53-Deficient Cells

  Open Access Article

  Norman L. Lehman, Emmy W. Verschuren, Jerry Y. Hsu, Athena M. Cherry and Peter K. Jackson
  Pages 1569 - 1573

• Cytostatic Activity of Paclitaxel in Coronary Artery Smooth Muscle Cells is Mediated Through Transient Mitotic Arrest Followed by Permanent Post-Mitotic Arrest: Comparison with Cancer Cells

  Open Access Article

  Mikhail V. Blagosklonny, Zoya N. Demidenko, Maria Giovino, Carmin Szynal, Elina Donskoy, Robert A. Herrmann, James J. Barry and Anne M. Whalen
  Pages 1574 - 1579

Letter to the Editor

• DUF1613 is a Novel Family of Eucaryotic AdoMet-Dependent Methyltransferases

  Lukasz Knizewski and Krzysztof Ginalski
  Pages 1580 - 1582