Table of Contents

Volume 4, Issue 9

  September 2005

  Pages 1131 - 1304

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• New and Old Functions of STAT3: A Pivitol Target for Individualized Treatment of Cancer

  G. Inghirami, R. Chiarle, W.J. Simmons, R. Piva, K. Schlessinger, D.E. Levy
  Pages 1131 - 1133

• The Role of CREB as a Proto-oncogene in Hematopoiesis

  Kentaro Kinjo, Salemiz Sandoval, Kathleen M. Sakamoto and Deepa B. Shankar
  Pages 1134 - 1135

• Search for Testicular Cancer Gene Hits Dead-End

  Angabin Matin and Joseph H. Nadeau
  Pages 1136 - 1138

• Hedgehogs as Negative Regulators of the Cell Cycle

  Carl Neumann
  Pages 1139 - 1140

• Apoptosis Through Targeted Activation of Caspase8 (“ATTAC-mice”): Novel Mouse Models of Inducible and Reversible Tissue Ablation

  Maria E. Trujillo, Utpal B. Pajvani and Philipp E. Scherer
  Pages 1141 - 1145

• The Making of the Liver: Competence in the Foregut Endoderm and Induction of Liver-Specific Genes

  Klaus H. Kaestner
  Pages 1146 - 1148

• Microtubule Associated Protein (MAP)-Tau: A Novel Mediator of Paclitaxel Sensitivity In Vitro and In Vivo

  P. Wagner, B. Wang, E. Clark, H. Lee, R. Rouzier and L. Pusztai
  Pages 1149 - 1152

• Regulation of HIF by Prolyl hydroxylases: Recruitment of the Candidate Tumor Suppressor Protein ING4

  Abdullah Ozer and Richard K. Bruick
  Pages 1153 - 1156

• Assembly of GMPCPP-Bound Tubulin into Helical Ribbons and Tubes and Effect of Colchicine

  Hong-Wei Wang, Sydney Long, K. Rose Finley and Eva Nogales
  Pages 1157 - 1160

Perspectives

• Ran-GTP regulates Kinetochore Attachment in Somatic Cells

  Alexei Arnaoutov and Mary Dasso
  Pages 1161 - 1165

• ATM-Mediated Phosphorylations Inhibit Mdmx/Mdm2 Stabilization by HAUSP in Favor of p53 Activation

  Erik Meulmeester, Yaron Pereg, Yosef Shiloh and Aart G. Jochemsen
  Pages 1166 - 1170

• Death-From-Cancer Signatures and Stem Cell Contribution to Metastatic Cancer

  Gennadi V. Glinsky
  Pages 1171 - 1175

• Poly(ADP-ribose) Polymerase (PARP-1) in Homologous Recombination and as a Target for Cancer Therapy

  Thomas Helleday, Helen E. Bryant and Niklas Schultz
  Pages 1176 - 1178

• MicroRNAs: Critical Regulators of Development, Cellular Physiology and Malignancy

  Joshua T. Mendell
  Pages 1179 - 1184

• Crosstalk Between Pten and Ras Signaling Pathways in Tumor Development

  Minh D. To, Jesus Perez-Losada, Jian-Hua Mao, Allan Balmain
  Pages 1185 - 1188

• Activating p38 MAPK: New Tricks for an Old Kinase

  Paul R. Mittelstadt, Jesús M. Salvador, Albert J. Fornace, Jr. and Jonathan D. Ashwell
  Pages 1189 - 1192

Reviews

• Repair of Double-Strand DNA Breaks by the Human Nonhomologous DNA End Joining Pathway: The Iterative Processing Model

  Yunmei Ma, Haihui Lu, Klaus Schwarz and Michael R. Lieber
  Pages 1193 - 1200

• Molecular Targets and Anticancer Potential of Indole-3-Carbinol and Its Derivatives

  Bharat B. Aggarwal and Haruyo Ichikawa
  Pages 1201 - 1215

• Good Timing in the Cell Cycle for Precise DNA Repair by BRCA1

  Stephen T Durant and Jac A Nickoloff
  Pages 1216 - 1222

Brief Reports

• DNA Replication Initiates at Different Sites in Early and Late S Phase within Human Ribosomal RNA Genes

  Frederick D. Coffman, Mai He, Mai-Ling Diaz and Stanley Cohen
  Pages 1223 - 1226

• The Abnormal Spindle-like, Microcephaly-associated (ASPM) Gene Encodes a Centrosomal Protein

  Xueyan Zhong, Limin Liu, Ailian Zhao, Gerd P. Pfeifer and Xingzhi Xu
  Pages 1227 - 1229

• Involvement of the SCF Complex in the Control of Cdh1 Degradation in S-phase

  Ramla Benmaamar and Michele Pagano
  Pages 1230 - 1232

Reports

• CDC25B Phosphorylation by Aurora A Occurs at the G2/M Transition and is Inhibited by DNA Damage

  Martine Cazales, Estelle Schmitt, Emilie Montembault, Christine Dozier, Claude Prigent and Bernard Ducommun
  Pages 1233 - 1238

• The Intracellular Tyrosine Kinase Brk Sensitizes Nontransformed Cells to Inducers of Apoptosis

  Andrea Haegebarth, Rafael Nunez and Angela L. Tyner
  Pages 1239 - 1246

• Blockage of NF-?B Induces Serine 15 Phosphorylation of Mutant p53 by JNK Kinase in Prostate Cancer Cells

  Luiz F Zerbini, Yihong Wang, Ricardo G. Correa, Je-Yoel Cho and Towia A Libermann
  Pages 1247 - 1253

• Human CDK2 Inhibition Modifies the Dynamics of Chromatin-Bound Minichromosome Maintenance Complex and Replication Protein A

  Yonghong Zhu, Yukio Ishimi, Marcel Tanudji and Emma Lees
  Pages 1254 - 1263

• p53 Codon 72 Alleles Influence the Response to Anticancer Drugs in Cells from Aged People by Regulating the Cell Cycle Inhibitor p21^WAF1

  Stefano Salvioli, Massimiliano Bonafé, Cristiana Barbi, Gianluca Storci, Chiara Trapassi, Francesca Tocco, Silvia Gravina, Matteo Rossi, Luca Tiberi, Chiara Mondello, Daniela Monti and Claudio Franceschi
  Pages 1264 - 1271

• Retinoblastoma Family 2 is Required In Vivo for the Tissue-Specific Repression of dE2F2 target Genes

  Olivier Stevaux, Dessislava K. Dimova, Jun-Yuan Ji, Nam Sung Moon, Maxim V. Frolov and Nicholas J. Dyson
  Pages 1272 - 1280

• APOBEC4, a New Member of the AID/APOBEC Family of Polynucleotide (Deoxy)Cytidine Deaminases Predicted by Computational Analysis

  Igor B. Rogozin, Malay K. Basu, I. King Jordan, Youri I. Pavlov and Eugene V. Koonin
  Pages 1281 - 1285

• Role of the Cell Cycle in the Pathobiology of Central Nervous System Trauma

  Ibolja Cernak, Bogdan Stoica, Kimberly R. Byrnes, Simone Di Giovanni and Alan I. Faden
  Pages 1286 - 1293

• Topoisomerase II Suppresses the Temperature Sensitivity of Saccharomyces cerevisiae pds5 Mutants, but not the Defect in Sister Chromatid Cohesion

  Cristina Aguilar, Christian Davidson, Melissa Dix, Kristen Stead, Ke Zheng, Theresa Hartman and Vincent Guacci
  Pages 1294 - 1304