Table of Contents

Volume 4, Issue 10

  October 2005

  Pages 1309 - 1456

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• Then Negative Regulation of Phosphoinositide 3-Kinase Signaling by p85 and Its Implication in Cancer

  Ji Luo and Lewis C. Cantley
  Pages 1309 - 1312

• ΔNp63α Levels Correlate with Clinical Tumor Response to Cisplatin

  Rachel Zangen, Edward Ratovitski and David Sidransky
  Pages 1313 - 1315

• The Arf Tumor Suppressor Regulates Platelet-Derived Growth Factor Receptor ? Signaling: A New View through the Eyes of Arf^-/- Mice

  J. Derek Thornton, Ricardo L.A. Silva, Amy C. Martin and Stephen X. Skapek
  Pages 1316 - 1319

• Telomere Sister Chromatid Exchange in Telomerase Deficient Murine Cells

  Yisong Wang, Richard J. Giannone and Yie Liu
  Pages 1320 - 1322

• Human Embryonic Stem Cells as a Model for Studying Epigenetic Regulation During Early Development

  Peter J. Rugg-Gunn, Anne C. Ferguson-Smith and Roger A. Pedersen
  Pages 1323 - 1326

• Oncogenic Remodeling of the Three-Dimensional Organization of the Interphase Nucleus: c-Myc Induces Telomeric Aggregates Whose Formation Precedes Chromosomal Rearrangements

  Sabine Mai and Yuval Garini
  Pages 1327 - 1331

• Drosophila Female Meiosis and Embryonic Syncytial Mitosis Use Specialized Cks and CDC20 Proteins for Cyclin Destruction

  Andrew Swan and Trudi Schüpbach
  Pages 1332 - 1334

• The Oncoprotein Gankyrin Negatively Regulates Both p53 and RB by Enhancing Proteasomal Degradation

  Hiroaki Higashitsuji, Yu Liu, R. John Mayer and Jun Fujita
  Pages 1335 - 1337

• Self-Renewal of the Adult Skeletal Muscle Satellite Cell

  Charlotte A. Collins and Terence A. Partridge
  Pages 1338 - 1341

Perspectives

• The Two Faces of NF?B in Cell Survival Responses

  Bonnie Graham and Spencer B. Gibson
  Pages 1342 - 1345

• Monitoring the Cell Cycle by Multi-Kinase-Dependent Regulation of Swe1/Wee1 in Budding Yeast

  Kyung S. Lee, Satoshi Asano, Jung-Eun Park, Krisada Sakchaisri and Raymond L. Erikson
  Pages 1346 - 1349

• Colorectal Cancer Progression: Integrin alphavbeta6 and the Epithelial-Mesenchymal Transition (EMT)

  Richard C. Bates
  Pages 1350 - 1352

• Stem Cell Regulation by the Haemopoietic Stem Cell Niche

  David N. Haylock and Susan K. Nilsson
  Pages 1353 - 1355

• Mechanisms of Tumor Suppression by the SCFFbw7

  Alex C. Minella and Bruce E. Clurman
  Pages 1356 - 1359

• Cardiomyocyte Proliferation: A Platform for Mammalian Cardiac Repair

  Felix B. Engel
  Pages 1360 - 1363

• p16INK4a as a Second Effector of the Telomere Damage Pathway

  Jacqueline J.L. Jacobs and Titia de Lange
  Pages 1364 - 1368

• Biomarkers to Predict Response to Epidermal Growth Factor Receptor Inhibitors

  Daphne A. Haas-Kogan, Michael D. Prados, Kathleen R. Lamborn, Tarik Tihan, Mitchel S. Berger and David Stokoe
  Pages 1369 - 1372

• Dynamics of Chromatin during the Repair of DNA Double-Strand Breaks

  Jessica A. Downs and Jacques Cote
  Pages 1373 - 1376

• Towards the Human Cancer Epigenome: A First Draft of Histone Modifications

  Mario F. Fraga and Manel Esteller
  Pages 1377 - 1381

Brief Reports

• Analysis of BRAF Mutation in Primary and Metastatic Melanoma

  Massimo Libra, Grazia Malaponte, Patrick M. Navolanic, Pietro Gangemi, Valentina Bevelacqua, Lidia Proietti, Bibiana Bruni, Franca Stivala, Maria C. Mazzarino, Salvatore Travali and James A. McCubrey
  Pages 1382 - 1384

• Low Concentrations of Taxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDC from Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leading to Aneuploidy

  Amy E. Ikui, Chia-Ping Huang Yang, Tomohiro Matsumoto and Susan Band Horwitz
  Pages 1385 - 1388

Reports

• Increased Protein Expression of the PTEN Tumor Suppressor in the Presence of Constitutively Active Notch-1

  William H. Chappell, Thomas D. Green, Justin D. Spengeman, James A. McCubrey, Shaw M. Akula and Fred E. Bertrand
  Pages 1389 - 1395

• Antisense Knockdown of Cyclin E does not affect the Midblastula Transition in Xenopus laevis Embryos

  Michael K. Slevin, Gillian Lyons-Levy, Daniel L. Weeks and Rebecca S. Hartley
  Pages 1396 - 1402

• Poliovirus Protein 3A Binds and Deregulates LIS1, Causing Block of Membrane Protein Trafficking and Deregulation of Cell Division

  Anna A. Kondratova, Nickolay Neznanov, Roman V. Kondratov and Andrei V. Gudkov
  Pages 1403 - 1410

• The N-terminal Regulatory Domain of Cyclin A Contains Redundant Ubiquitination Targeting Sequences and Acceptor Sites

  Tsz Kan Fung, Cain H. Yam and Randy Y.C. Poon
  Pages 1411 - 1420

• The Acidic Tail domain of Human Cdc34 is Required for p27Kip1 Ubiquitination and Complementation of a cdc34 Temperature Sensitive Yeast Strain

  Karen Block, Srikanth Appikonda, Horng-Ru Lin, Joanna Bloom, Michele Pagano and P. Renee Yew
  Pages 1421 - 1427

• Inhibition of the ATR/Chk1 Pathway Induces a p38-Dependent S-phase Delay in Mouse ES Cells

  Ludmila Jirmanova, Dmitry V. Bulavin and Albert J. Fornace, Jr.
  Pages 1428 - 1434

• Human Cytomegalovirus Inactivates the G0/G1-APC/C Ubiquitin Ligase by Cdh1 Dissociation

  Lüder Wiebusch, Miriam Bach, Ralf Uecker and Christian Hagemeier
  Pages 1435 - 1439

• AEC-Associated p63 Mutations Lead to Alternative Splicing/Protein Stabilization of p63 and Modulation of Notch Signaling

  Yi-Ping Huang, Yuriy Kim, Zhaobo Li, Tanya Fomenkov, Alexey Fomenkov and Edward A. Ratovitski
  Pages 1440 - 1447

• Spindle Checkpoint Maintenance Requires Ame1 and Okp1

  Isabelle Pot, James Knockleby, Victoria Aneliunas, Thao Nguyen, Sonia Ah-Kye, Gregory Liszt, Michael Snyder, Philip Hieter and Jackie Vogel
  Pages 1448 - 1456