Table of Contents

Volume 3, Issue 2

  February 2004

  Pages 95 - 222

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• Evidence of Mnt-Myc Antagonism Revealed by Mnt Gene Deletion

  Peter J. Hurlin, Zi-Qiang Zhou, Kazuhito Toyo-oka, Sara Ota, William L. Walker, Shinji Hirotsune, and Anthony Wynshaw-Boris
  Pages 95 - 97

• A New Kind of Prion: A Modified Protein Necessary for Its Own Modification

  B. Tibor Roberts and Reed B. Wickner
  Pages 98 - 100

• Muscle-Derived Stem Cells

  Baohong Cao and Johnny Huard
  Pages 101 - 104

• Cdk5 Phosphorylation of FAK Regulates Centrosome-Associated Microtubules and Neuronal Migration

  Zhigang Xie and Li-Huei Tsai
  Pages 105 - 108

• Deregulated Repression of c-Jun Provides a Potential Link to its Role in Tumorigenesis

  Carsten Weiss and Dirk Bohmann
  Pages 109 - 111

• Auto-Acetylation of Transcription Factors as a Control Mechanism in Gene Expression

  Chu H. Choi, Zachary F. Burton and Anny Usheva
  Pages 112 - 113

• When Pol I Goes into High Gear: Processive DNA Synthesis by Pol I in the Cell

  Manel Camps and Lawrence A. Loeb
  Pages 114 - 116

• Remodelling the Rad9 Checkpoint Complex: Preparing Rad53 for Action

  Michael van den Bosch and Noel F. Lowndes
  Pages 117 - 120

• Genetic Reprogramming by Retroviruses: Enhanced Suppression of Translational Termination

  Stephen P. Goff
  Pages 121 - 123

• A Novel Replication Arrest Pathway in Response to DNA Damage

  M.P. Stokes and W.M. Michael
  Pages 124 - 125

• The Polo-Box Domain: A Molecular Integrator of Mitotic Kinase Cascades and Polo-like Kinase Function

  Drew M. Lowery, Duaa H. Mohammad, Andrew E. H. Elia and Michael B. Yaffe
  Pages 126 - 129

• Attach First, then Detach: A Role for Cyclin B-Dependent Kinase 1 in Coordinating Proteolysis with Spindle Assembly

  Vincenzo D'Angiolella and Domenico Grieco
  Pages 130 - 131

Perspectives

• Role of p21WAF1 in the Cellular Response to UV

  Rati Fotedar, Mourad Bendjennat and Arun Fotedar
  Pages 132 - 135

• To Be or Not to Be...Ubiquitinated?

  Joanna Bloom and Michele Pagano
  Pages 136 - 138

• Thermodynamic Cooperativity and Kinetic Proofreading in DNA Damage Recognition and Repair

  Joyce T. Reardon and Aziz Sancar
  Pages 139 - 142

• b-Catenin and Cyclin D1: Connecting Development to Breast Cancer

  Tracey M. Rowlands, Irina V. Pechenkina, Sarah Hatsell and Pamela Cowin
  Pages 143 - 146

• H2AX May Function as an Anchor to Hold Broken Chromosomal DNA Ends in Close Proximity

  Craig H. Bassing and Frederick W. Alt
  Pages 147 - 148

Intro: Spotlight on HIF

• HIF-1: A Target For Cancer, Ischemia and Inflammation—Too Good to be True?

  Giovanni Melillo
  Pages 149 - 150

Spotlight on HIF

• HIF-1’s Relationship to Oxygen: Simple yet Sophisticated

  Patrick Maxwell
  Pages 151 - 154

• Dead Cells Don’t Form Tumors: HIF-Dependent Cytotoxins

  Patrick D. Sutphin, Denise A. Chan and Amato J. Giaccia
  Pages 155 - 158

• Hypoxia Inducible Carbonic Anhydrase IX, Marker of Tumour: Hypoxia, Survival Pathway and Therapy Target

  Christian Potter and Adrian L Harris
  Pages 159 - 162

• An Unexpected Role for Hypoxic Response: Oxygenation and Inflammation

  Carole Peyssonaux and Randall S. Johnnson
  Pages 163 - 166

• Targeting Topoisomerase 1 to inhibit Hypoxia Inducible Factor 1

  Annamaria Rapisarda, Robert H. Shoemaker, and Giovanni Melillo
  Pages 167 - 170

Views and Commentaries

• Role of Raf Isoforms in Signal Transduction Pathways Relevant to Leukemia Cell Proliferation

  Martyn K. White
  Pages 171 - 173

Brief Report

• FANCL Replaces BRCA1 as the Likely Ubiquitin Ligase Responsible for FANCD2 Monoubiquitination

  Amom Ruhikanta Meetei, Zhijiang Yan and Weidong Wang
  Pages 174 - 176

Reports

• Structure Predictions and Interaction Studies Indicate Homology of Separase N-Terminal Regulatory Domains and Drosophila THR

  Hubert Jäger, Bettina Herzig, Alf Herzig, Heinrich Sticht, Christian F. Lehner and Stefan Heidmann
  Pages 177 - 183

• B-Raf and Insulin Synergistically Prevent Apoptosis and Induce Cell Cycle Progression in Hematopoietic Cell

  John G. Shelton, Fumin Chang, John T. Lee, Richard A. Franklin, Linda S. Steelman and James A. McCubrey
  Pages 184 - 191

• Differential Kinetochore Requirements for Establishment and Maintenance of the Spindle Checkpoint Are Dependent on the Mechanism of Checkpoint Activation in Saccharomyces cerevisiae

  Atasi Poddar, Jewel A. Daniel, John R. Daum and Daniel J. Burke
  Pages 192 - 199

• Tocotrienol-Rich Fraction of Palm Oil Activates p53, Modulates Bax/Bcl2 Ratio and Induces Apoptosis Independent of Cell Cycle Association

  Mukesh K. Agarwal, Munna L. Agarwal, Mohammad Athar and Sanjay Gupta
  

• Altered Expression of Chk1 Disrupts Cell Cycle Remodeling at the Midblastula Transition in Xenopus laevis Embryos

  Matthew J. Petrus, Dayna E. Wilhelm, Monica Murakami, Nicholas C. Kappas, Ayesha D. Carter, Brian N. Wroble and Jill C. Sible
  Pages 200 - 204

• Cell-Cycle Regulation of NF-YC Nuclear Localization

  Mattia Frontini, Carol Imbriano, Isabella Manni and Roberto Mantovani
  Pages 205 - 210

• Persistence Length of Chromatin Determines Origin Spacing in Xenopus Early-Embryo DNA Replication: Quantitative Comparisons between Theory and Experiment

  Suckjoon Jun, John Herrick, Aaron Bensimon, and John Bechhoefer
  Pages 211 - 217

• Flavopiridol inhibits the Growth of GL261 Gliomas In Vivo: Implications for Malignant Glioma Therapy

  Elizabeth W. Newcomb, Cristina Tamasdan, Yolanda Entzminger, Elizabeth Arena, Tona Schnee, Mimi Kim, Diana Crisan, Yevgeniy Lukyanov, Douglas C. Miller and David Zagzag
  Pages 218 - 222