Table of Contents

Volume 3, Issue 12

  December 2004

  Pages 1477 - 1650

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• Epithelial-Mesenchymal Transition: NF-κB Takes Center Stage

  Margit A. Huber, Hartmut Beug and Thomas Wirth
  Pages 1477 - 1480

• Regulation of Cell Cycle in Hematopoietic Stem Cells by the Niche

  Atsushi Hirao, Fumio Arai and Toshio Suda
  Pages 1481 - 1483

• Heat Shock Protein 70 Promotes Cancer Cell Viability by Safeguarding Lysosomal Integrity

  Mads Gyrd-Hansen, Jesper Nylandsted and Marja Jäättelä
  Pages 1484 - 1485

• Abl Oncogene Bypasses Normal Regulation of JAK/STAT Activation

  André Limnander and Paul B. Rothman
  Pages 1486 - 1488

• Delineating the Hepatocyte's Hematopoietic Fusion Partner

  Holger Willenbring and Markus Grompe
  Pages 1489 - 1491

• Stress-Induced p53 Runs a Direct Mitochondrial Death Program: Its Role in Physiologic and Pathophysiologic Stress Responses In Vivo

  Susan Erster and Ute M. Moll
  Pages 1492 - 1495

• Inhibition of Mutant EGF Receptors by Gefitinib: Targeting an Achilles’ Heel of Lung Cancer

  Jeffrey Settleman
  Pages 1496 - 1497

• Protein Phosphorylation as a Key Mechanism for the Regulation of BCL-3 Activity

  Patrick Viatour, Marie-Paule Merville, Vincent Bours and Alain Chariot
  Pages 1498 - 1501

• Pharmacokinetic Resistance to Imatinib Mesylate: Role of the ABC Drug Pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the Oral Bioavailability of Imatinib

  Herman Burger and Kees Nooter
  Pages 1502 - 1505

Perspectives

• Red Light, Green Light: Signals That Control Endothelial Cell Proliferation during Embryonic Vascular Development

  Brenda L. Bohnsack and Karen K. Hirschi
  Pages 1506 - 1511

• Wnt and Cyclooxygenase-2 Cross-talk Accelerates Adenoma Growth

  Dingzhi Wang, Jason R. Mann and Raymond N. DuBois
  Pages 1512 - 1515

• Multiple Roles for Cysteine Cathepsins in Cancer

  Johanna A. Joyce and Douglas Hanahan
  Pages 1516 - 1519

• JNK2: A Negative Regulator of Cellular Proliferation

  Kanaga Sabapathy and Erwin F.Wagner
  Pages 1520 - 1523

• NF-κB and JNK: An Intricate Affair

  Concetta Bubici, Salvatore Papa, Can G. Pham, Francesca Zazzeroni and Guido Franzoso
  Pages 1524 - 1529

Reviews

• Hsp90 Activation and Cell Cycle Regulation

  Francis Burrows, Hong Zhang and Adeela Kamal
  Pages 1530 - 1536

• Flavopiridol, An Inhibitor of Transcription: Implications, Problems and Solutions

  Mikhail V. Blagosklonny
  Pages 1537 - 1542

Reports

• p53 Prevents the Accumulation of Double-Strand DNA Breaks at Stalled-Replication Forks Induced by UV in Human Cells

  Shoshana Squires, Julia A. Coates, Michal Goldberg, Lorraine H. Toji, Stephen P. Jackson, Duncan J. Clarke and Robert T. Johnson

  Pages 1543 - 1557

• Initiation of Colorectal Cancer: Where do the Two Hits Hit?

  Natalia L. Komarova and Liming Wang
  Pages 1558 - 1565

• Pro- and Anti-Apoptotic Effects of an Inhibitor of Chymotrypsin-Like Serine Proteases

  Malcolm A. King, Dorota Halicka and Zbigniew Darzynkiewicz
  Pages 1566 - 1571

• Regulation of Cyclin E Protein Levels through E2F-Mediated Inhibition of Degradation

  Deborah Pajalunga and Marco Crescenzi
  Pages 1572 - 1578

• ATR and ATM-Dependent Movement of BLM Helicase during Replication Stress Ensures Optimal ATM Activation and 53BP1 Focus Formation

  Albert R. Davalos, Patrick Kaminker, Rhonda K. Hansen and Judith Campisi
  Pages 1579 - 1586

• Altered Sumoylation of p63α Contributes to the Split-Hand/Foot Malformation Phenotype

  Yi-Ping Huang, Guojun Wu, Zhongmin Guo, Motonobu Osada,Tanya Fomenkov, Hannah Lui Park, Barry Trink, DavidSidransky, Alexey Fomenkov and Edward A. Ratovitski
  Pages 1587 - 1596

• Genistein Induces G2 Arrest in Malignant B Cells by Decreasing IL-10 Secretion

  Amal Mansour, Brian McCarthy, Stephan K Schwander, Victor Chang, Sergei Kotenko, Sreekrishna Donepudi, Janet Lee and Elizabeth Raveche
  Pages 1597 - 1605

• Cell Death Inhibiting RNA (CDIR) Modulates IFN-γ-Stimulated Sensitization to Fas/CD95/Apo-1 and TRAIL/Apo-2L-Induced Apoptosis

  Ksenya Shchors, Fruma Yehiely and Louis P. Deiss
  Pages 1606 - 1611

• Ufd2, a Novel Autoantigen in Scleroderma, Regulates Sister Chromatid Separation

  Sarah Spinette, Christoph Lengauer, James A. Mahoney, Prasad V. Jallepalli, Zhenghe Wang, Livia Casciola-Rosen and Antony Rosen
  Pages 1612 - 1618

• A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells upon Neural Induction

  Pascale Perry, Stephan Sauer, Nathalie Billon, William D. Richardson, Mikhail Spivakov, Gary Warnes, Frederick J. Livesey, Matthias Merkenschlager, Amanda G. Fisher and Véronique Azuara
  Pages 1619 - 1624

• Comparative Genomics, Evolution and Origins of the Nuclear Envelope and Nuclear Pore Complex

  Berend Mans, Vivek Anantharaman, L. Aravind and Eugene V. Koonin
  Pages 1625 - 1650