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Table of Contents

August 15, 2008

volume 7| issue 16



News

Remarkable features of tiny RNA molecules: Highlights of revolutionary discoveries on the path from the bench to bedside

Gennadi V. Glinsky
Volume: 7 | Issue: 16 | Page 2451

Open Access Article



Extra Views

Modulation of the "blood-tumor" barrier improves immunotherapy

Mitali Manzur, Juliana Hamzah and Ruth Ganss
Volume: 7 | Issue: 16 | Pages: 2452 - 2455

Strap: A versatile transcription co-factor

Danmei Xu and Nicholas B La Thangue
Volume: 7 | Issue: 16 | Pages: 2456 - 2457

Perspectives

microRNA(interference) networks are embedded in the gene regulatory networks

Letizia Pitto, Andrea Ripoli, Federico Cremisi and Giuseppe Rainaldi
Volume: 7 | Issue: 16 | Pages: 2458 - 2461

Mechanotransduction and anoikis: Death and the homeless cell

Zhenyi Ma, Zhe Liu, David P. Myers and Lance S. Terada
Volume: 7 | Issue: 16 | Pages: 2462 - 2465

Targeting the eIF4F translation initiation complex for cancer therapy

Bruce W. Konicek, Chad A. Dumstorf and Jeremy R. Graff
Volume: 7 | Issue: 16 | Pages: 2466 - 2471

Reviews

RecQ family helicases in genome stability: Lessons from gene disruption studies in DT40 cells

Masayuki Seki, Makoto Otsuki , Yutaka Ishii , Shusuke Tada and Takemi Enomoto
Volume: 7 | Issue: 16 | Pages: 2472 - 2478

Open Access Article


Cell death specification in C. elegans

Erin Peden, Darrell J. Killian and Ding Xue
Volume: 7 | Issue: 16 | Pages: 2479 - 2484

Spotlight on microRNA

MicroRNAs and cancer: An overview

Pedro P. Medina and Frank J. Slack
Volume: 7 | Issue: 16 | Pages: 2485 - 2492

Functional integration of microRNAs into oncogenic and tumor suppressor pathways

Craig D. Lotterman, Oliver A. Kent and Joshua T. Mendell
Volume: 7 | Issue: 16 | Pages: 2493 - 2499

Lessons from microRNA mutants in worms, flies and mice

Peter Smibert and Eric C. Lai
Volume: 7 | Issue: 16 | Pages: 2500 - 2508

Reports

Hearts lacking caveolin-1 develop hypertrophy with normal cardiac substrate metabolism

Ayanna S. Augustus, Jonathan Buchanan, Ellen Gutman, Giuseppe Rengo, Richard G. Pestell, Paolo Fortina, Walter J. Koch, Andre Bensadoun, E. Dale Abel and Michael P. Lisanti
Volume: 7 | Issue: 16 | Pages: 2509 - 2518

p53-Ubl fusions as models of ubiquitination, sumoylation and neddylation of p53

Stephanie Carter and Karen H. Vousden
Volume: 7 | Issue: 16 | Pages: 2519 - 2528

Open Access Article


A role for Drosophila Polo protein in chromosome resolution and segregation during mitosis

Susana Godinho and Álvaro A. Tavares
Volume: 7 | Issue: 16 | Pages: 2529 - 2534

p53 binding to the p21 promoter is dependent on the nature of DNA damage

Ewelina Bodzak , Michael D. Blough , Patrick W.K. Lee and Richard Hill
Volume: 7 | Issue: 16 | Pages: 2535 - 2543

GFP reporter mice for the retinoblastoma-related cell cycle regulator p107

Deborah L. Burkhart, Patrick Viatour, Victoria M. Ho and Julien Sage
Volume: 7 | Issue: 16 | Pages: 2544 - 2552

Open Access Article


Autocrine regulation of glioblastoma cell-cycle progression, viability and radioresistance through the VEGF-VEGFR2 (KDR) interplay

Petra Knizetova, Jiri Ehrmann, Alice Hlobilkova, Iveta Vancova , Ondrej Kalita, Zdenek Kolar and Jiri Bartek
Volume: 7 | Issue: 16 | Pages: 2553 - 2561

Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex

Pradeep S. Pallan and Martin Egli
Volume: 7 | Issue: 16 | Pages: 2562 - 2569

An SNP-guided microRNA map of fifteen common human disorders identifies a consensus disease phenocode aiming at principal components of the nuclear import pathway

Gennadi Glinsky
Volume: 7 | Issue: 16 | Pages: 2570 - 2583

Open Access Article


Mitochondrially targeted wild-type p53 induces apoptosis in a solid human tumor xenograft model

Gustavo Palacios, Howard C. Crawford, Angelina Vaseva and Ute M. Moll
Volume: 7 | Issue: 16 | Pages: 2584 - 2590

Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer

Dmitri Lodygin, Valery Tarasov, Alexey Epanchintsev, Carola Berking, Tatjana Knyazeva, Henrike Körner, Piotr Knyazev, Joachim Diebold and Heiko Hermeking
Volume: 7 | Issue: 16 | Pages: 2591 - 2600

Open Access Article


Mechanistic principles of chromatin remodeling guided by siRNAs and miRNAs

Susana Gonzalez, David G. Pisano and Manuel Serrano
Volume: 7 | Issue: 16 | Pages: 2601 - 2608