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Table of Contents

15 December 2007

volume 6| issue 24



Conceptual Review

Paradoxes of Aging

Mikhail V. Blagosklonny
Volume: 6 | Issue: 24 | Pages: 2997 - 3003

Extra Views

A Cul3-Based E3 Ligase Regulates Mitosis and is Required to Maintain the Spindle Assembly Checkpoint in Human Cells

Izabela Sumara and Matthias Peter
Volume: 6 | Issue: 24 | Pages: 3004 - 3010

All Roads Lead to mTOR: Integrating Inflammation and Tumor Angiogenesis

Dung-Fang Lee and Mien-Chie Hung
Volume: 6 | Issue: 24 | Pages: 3011 - 3014

Multiple Mechanisms for p27Kip1 Translocation and Degradation

Etsuo Susaki and Keiichi I. Nakayama
Volume: 6 | Issue: 24 | Pages: 3015 - 3020

Chemosensitizing Anti-Cancer Activity of LFM-A13, a Leflunomide Metabolite Analog Targeting Polo-like Kinases

Fatih M. Uckun
Volume: 6 | Issue: 24 | Pages: 3021 - 3026

The Dissection of Human Autosomal Recessive Osteopetrosis Identifies an Osteoclast-Poor Form Due to RANKL Deficiency

Annalisa Frattini, Paolo Vezzoni, Anna Villa and Cristina Sobacchi
Volume: 6 | Issue: 24 | Pages: 3027 - 3033

Revealing a Role of MicroRNAs in the Regulation of the Biological Clock

Hai-Ying Mary Cheng and Karl Obrietan
Volume: 6 | Issue: 24 | Pages: 3034 - 3038

Perspectives

CDC25A Levels Determine the Balance of Proliferation and Checkpoint Response

Dipankar Ray and Hiroaki Kiyokawa
Volume: 6 | Issue: 24 | Pages: 3039 - 3042

Open Access Article


Regulation of Mitochondrial Morphological Dynamics During Apoptosis by Bcl-2 family proteins: A Key in Bak?

Craig Brooks and Zheng Dong
Volume: 6 | Issue: 24 | Pages: 3043 - 3047

Does Caspase Inhibition Promote Clonogenic Tumor Growth?

Ute Fischer, Katja Janssen and Klaus Schulze-Osthoff
Volume: 6 | Issue: 24 | Pages: 3048 - 3053

Prostaglandin E2: Making More of Your Marrow

Allegra M. Lord, Trista E. North and Leonard I. Zon
Volume: 6 | Issue: 24 | Pages: 3054 - 3057

Review

Phosphatases, DNA Damage Checkpoints and Checkpoint Deactivation

Johanna Heideker, Ewa T. Lis and Floyd E. Romesberg
Volume: 6 | Issue: 24 | Pages: 3058 - 3064

Brief Report

CDK2 is Dispensable for Adult Hippocampal Neurogenesis

Renaud Vandenbosch, Laurence Borgs, Pierre Beukelaers, Agnès Foidart, Laurent Nguyen, Gustave Moonen, Cyril Berthet, Philipp Kaldis, Vittorio Gallo, Shibeshih Belachew and Brigitte Malgrange
Volume: 6 | Issue: 24 | Pages: 3065 - 3069

Report

The E3 Ubiquitin Ligase EDD Regulates S-Phase and G2/M DNA Damage Checkpoints

Marcia A. Munoz, Darren N. Saunders, Michelle J. Henderson, Jennifer L. Clancy, Amanda J. Russell, Gillian Lehrbach, Elizabeth A. Musgrove, Colin K.W. Watts and Robert L. Sutherland
Volume: 6 | Issue: 24 | Pages: 3070 - 3077

Bilirubin Inhibits Tumor Cell Growth via Activation of ERK

Robert Ollinger, Pamela Kogler, Jakob Troppmair, Martin Hermann, Martin Wurm, Astrid Drasche, Ingmar Konigsrainer, Albert Amberger, Helmut Weiss, Dietmar Ofner, Fritz H. Bach and Raimund Margreiter
Volume: 6 | Issue: 24 | Pages: 3078 - 3085

Staurosporine Sensitizes T Lymphoma Cells to Glucocorticoid-Induced Apoptosis: Role of Nur77 and Bcl-2

Shlomit Kfir, Ronit Vogt Sionov, Elazar Zafrirv, Yael Zilberman and Eitan Yefenof
Volume: 6 | Issue: 24 | Pages: 3086 - 3096

Cytostatic and Cytotoxic Properties of Amphinase: A Novel Cytotoxic Ribonuclease from Rana pipiens Oocytes

Barbara Ardelt, Wojciech Ardelt, Piotr Pozarowski, Jan Kunicki, Kuslima Shogen and Zbigniew Darzynkiewicz
Volume: 6 | Issue: 24 | Pages: 3097 - 3102

Apaf-1 Deficiency Causes Chromosomal Instability

Shahul Mouhamad, Lorenzo Galluzzi, Yael Zermati, Maria Castedo and Guido Kroemer
Volume: 6 | Issue: 24 | Pages: 3103 - 3107

High NaCl Promotes Cellular Senescence

Natalia I. Dmitrieva and Maurice B. Burg
Volume: 6 | Issue: 24 | Pages: 3108 - 3113

The Cyclin-Dependent Kinase Inhibitor Seliciclib (R-roscovitine; CYC202) Decreases the Expression of Mitotic Control Genes and Prevents Entry into Mitosis

Steven R. Whittaker, Robert H. te Poele, Florence Chan, Spiros Linardopoulos, Michael I. Walton, Michelle D. Garrett and Paul Workman
Volume: 6 | Issue: 24 | Pages: 3114 - 3131

Nitric Oxide Coordinates Cell Proliferation and Cell Movements During Early Development of Xenopus

Natalia Peunova, Vladimir Scheinker, Kandasamy Ravi and Grigori Enikolopov
Volume: 6 | Issue: 24 | Pages: 3132 - 3144

Open Access Article



Letter to the Editor

Multiple Kinases and System Robustness: A Link Between Cdc37 and Genome Integrity

Avrom J. Caplan, Avi Ma'ayan and Ian M. Willis
Volume: 6 | Issue: 24 | Pages: 3145 - 3147

Open Access Article