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Table of Contents

15 july 2006

volume 5| issue 14



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New Directions for Neurodegenerative Disease Therapy: Using Chemical Compounds to Boost the Formation of Mutant Protein Inclusions

Ruth A. Bodner, David E. Housman and Aleksey G. Kazantsev
Volume: 5 | Issue: 14 | Pages: 1477 - 1480

Open Access Article


BRCA1-Mediated Ubiquitylation

Simon J. Boulton
Volume: 5 | Issue: 14 | Pages: 1481 - 1486

APC/C-Mediated Degradation in Early Mitosis: How to Avoid Spindle Assembly Checkpoint Inhibition

Andrew M. Fry and Hiroyuki Yamano
Volume: 5 | Issue: 14 | Pages: 1487 - 1491

Open Access Article


A Novel Link Between SUMO Modification and Cancer Metastasis

Sung Hee Baek
Volume: 5 | Issue: 14 | Pages: 1492 - 1495

The Double Life of UPF1 in RNA and DNA Stability Pathways

Claus M. Azzalin and Joachim Lingner
Volume: 5 | Issue: 14 | Pages: 1496 - 1498

Partitioning Viral Genomes in Mitosis: Same Idea, Different Targets

Alison A. McBride, Jaquelline G. Oliveira and Maria G. McPhillips
Volume: 5 | Issue: 14 | Pages: 1499 - 1502

Open Access Article



Perspectives

Transcriptional Regulation by the Proteasome as a Mechanism for Cellular Protein

Kathryn L. Auld and Pamela A. Silver
Volume: 5 | Issue: 14 | Pages: 1503 - 1505

Novel Functions for Cell Cycle Genes in Nervous System Development

Kelly A. McClellan and Ruth S. Slack
Volume: 5 | Issue: 14 | Pages: 1506 - 1513

ERK and Beyond: Insights from B-Raf and Raf-1 Conditional Knockouts

Gergana Galabova-Kovacs, Andrea Kolbus, Dana Matzen, Katrin Meiss, Daniela Piazzolla, Cristina Rubiolo, Katharina Steinitz and Manuela Baccarini
Volume: 5 | Issue: 14 | Pages: 1514 - 1518

Deciphering the Mammary Epithelial Cell Hierarchy

John Stingl, Afshin Raouf, Peter Eirew and Connie J. Eaves
Volume: 5 | Issue: 14 | Pages: 1519 - 1522

Regulation of PTEN Function as a PIP3 Gatekeeper Through Membrane Interaction

Francisca Vazquez and Peter Devreotes
Volume: 5 | Issue: 14 | Pages: 1523 - 1527

Differentiation of Neuronal Cells in Fragile X Syndrome

Maija Castrén
Volume: 5 | Issue: 14 | Pages: 1528 - 1530

Review

Unique Conditionally Replication Competent Bipartite Adenoviruses—Cancer Terminator Viruses (CTV): Efficacious Reagents for Cancer Gene Therapy

Devanand Sarkar, Zao-zhong Su and Paul B. Fisher
Volume: 5 | Issue: 14 | Pages: 1531 - 1536

Report

A Two-Hit Mechanism for Pre-Mitotic Arrest of Cancer Cell Proliferation by a Polyamide-Alkylator Conjugate

David Alvarez, C. James Chou, Lucia Latella, Samantha G. Zeitlin, Sherman Ku, Pier Lorenzo Puri, Peter B. Dervan and Joel M. Gottesfeld
Volume: 5 | Issue: 14 | Pages: 1537 - 1548

Budding Yeast Sae2 is an In Vivo Target of the Mec1 and Tel1 Checkpoint Kinases During Meiosis

Hugo Cartagena-Lirola, Ilaria Guerini, Valeria Viscardi, Giovanna Lucchini and Maria Pia Longhese
Volume: 5 | Issue: 14 | Pages: 1549 - 1559

The Receptor Tyrosine Kinase Met and Its Ligand Hepatocyte Growth Factor are Clustered at Excitatory Synapses and Can Enhance Clustering of Synaptic Proteins

Stephanie J. Tyndall and Randall S. Walikonis
Volume: 5 | Issue: 14 | Pages: 1560 - 1568

Open Access Article


Overexpression of the Anaphase Promoting Complex/Cyclosome Inhibitor Emi1 Leads to Tetraploidy and Genomic Instability of p53-Deficient Cells

Norman L. Lehman, Emmy W. Verschuren, Jerry Y. Hsu, Athena M. Cherry and Peter K. Jackson
Volume: 5 | Issue: 14 | Pages: 1569 - 1573

Open Access Article


Cytostatic Activity of Paclitaxel in Coronary Artery Smooth Muscle Cells is Mediated Through Transient Mitotic Arrest Followed by Permanent Post-Mitotic Arrest: Comparison with Cancer Cells

Mikhail V. Blagosklonny, Zoya N. Demidenko, Maria Giovino, Carmin Szynal, Elina Donskoy, Robert A. Herrmann, James J. Barry and Anne M. Whalen
Volume: 5 | Issue: 14 | Pages: 1574 - 1579

Open Access Article



Letter to the Editor

DUF1613 is a Novel Family of Eucaryotic AdoMet-Dependent Methyltransferases

Lukasz Knizewski and Krzysztof Ginalski
Volume: 5 | Issue: 14 | Pages: 1580 - 1582