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Table of Contents

November 2005

volume 4| issue 11



Extra Views

Mechanisms of Protein Degradation: An Odyssey with ODC

Chaim Kahana, Gad Asher and Yosef Shaul
Volume: 4 | Issue: 11 | Pages: 1461 - 1464

Could MYC Induction of Mitochondrial Biogenesis be linked to ROS Production and Genomic Instability?

Chi V. Dang, Feng Li and Linda A. Lee
Volume: 4 | Issue: 11 | Pages: 1465 - 1466

Fine-Tuning the Chromosome Ends: The Last Base of Human Telomeres

Agnel J. Sfeir, Jerry W. Shay and Woodring E. Wright
Volume: 4 | Issue: 11 | Pages: 1467 - 1470

Setting the Record Straight on Data Supporting Postnatal Oogenesis in Female Mammals

Joshua Johnson, Malgorzata Skaznik-Wikiel, Ho-Joon Lee, Yuichi Niikura, Jacqueline Canning Tilly and Jonathan L. Tilly
Volume: 4 | Issue: 11 | Pages: 1471 - 1477

Nuclear Localized Phosphorylated FADD Induces Cell Proliferation and is Associated with Aggressive Lung Cancer

Mahaveer S. Bhojani, Guoan Chen, Brian D. Ross, David G. Beer and Alnawaz Rehemtulla
Volume: 4 | Issue: 11 | Pages: 1478 - 1481

Perspectives

KLP10A and KLP59C: The Dynamic Duo of Microtubule Depolymerization

David J. Sharp, Vito Mennella and Daniel W. Buster
Volume: 4 | Issue: 11 | Pages: 1482 - 1485

New Insights into TAFs as Regulators of Cell Cycle and Signalling Pathways

Irwin Davidson, Dominique Kobi, Anas Fadloun, and Gabrielle Mengus
Volume: 4 | Issue: 11 | Pages: 1486 - 1490

Cell Cycle Sibling Rivalry: Cdc2 Versus Cdk2

Philipp Kaldis and Eiman Aleem
Volume: 4 | Issue: 11 | Pages: 1491 - 1494

The Mitotic Checkpoint in Cancer Therapy

Weikang Tao
Volume: 4 | Issue: 11 | Pages: 1495 - 1498

Growth Control Under Stress: mTOR Regulation through the REDD1-TSC Pathway

Leif W. Ellisen
Volume: 4 | Issue: 11 | Pages: 1500 - 1502

Ras-Raf Signaling Needs Prohibitin

Krishnaraj Rajalingam and Thomas Rudel
Volume: 4 | Issue: 11 | Pages: 1503 - 1505

Cancer Pharmacogenomics May Require Both Qualitative and Quantitative Approaches

Qing Cheng and William E. Evans
Volume: 4 | Issue: 11 | Pages: 1506 - 1509

Loading and Unloading: Orchestrating Centrosome Duplication and Spindle Assembly by Ran/Crm1

Anuradha S. Budhu and Xin W. Wang
Volume: 4 | Issue: 11 | Pages: 1510 - 1514

Mitotic Entry: A Matter of Oscillating Destruction

Florian Bassermann, Christian Peschel and Justus Duyster
Volume: 4 | Issue: 11 | Pages: 1515 - 1517

Teratogens as Anticancer Drugs

Mikhail V. Blagosklonny
Volume: 4 | Issue: 11 | Pages: 1518 - 1521

Review

Oncogenic β-Catenin Signaling Networks in Colorectal Cancer

Serge Y. Fuchs, Andrei V. Ougolkov, Vladimir S. Spiegelman and Toshinari Minamoto
Volume: 4 | Issue: 11 | Pages: 1522 - 1539

mTOR, A New Therapeutic Target in Acute Myeloid Leukemia

Récher Christian, Dos Santos Cédric, Demur Cécile and Payrastre Bernard.
Volume: 4 | Issue: 11 | Pages: 1540 - 1549

What is the Role of Tubular Epithelial Cell Apoptosis in Polycystic Kidney Disease (PKD)?

Charles L. Edelstein
Volume: 4 | Issue: 11 | Pages: 1550 - 1554

Special Report

Evidence That the Yeast Spindle Assembly Checkpoint Has a Target Other Than the Anaphase Promoting Complex

Catherine A. Andrews, Laura A. Díaz-Martínez, Juan F. Giménez-Abián and Duncan J Clarke
Volume: 4 | Issue: 11 | Pages: 1555 - 1557

Proteasome Activity is Required for Centromere Separation Independently of Securin Degradation in Human Cells

Juan F. Giménez-Abián, Laura A. Díaz-Martínez, Karin G. Wirth, Consuelo De la Torre and Duncan J. Clarke
Volume: 4 | Issue: 11 | Pages: 1558 - 1560

Regulated Separation of Sister Centromeres depends on the Spindle Assembly Checkpoint but not on the Anaphase Promoting Complex/Cyclosome

Juan F. Giménez-Abián, Laura A. Díaz-Martínez, Karin G. Wirth, Catherine A. Andrews, Gonzalo Giménez-Martín and Duncan J. Clarke
Volume: 4 | Issue: 11 | Pages: 1561 - 1575

Separase is Required at Multiple Pre-Anaphase Cell Cycle Stages in Human Cells

Juan F. Giménez-Abián, Laura A. Díaz-Martínez, Irene C. Waizenegger, Gonzalo Giménez-Martín and Duncan J. Clarke
Volume: 4 | Issue: 11 | Pages: 1576 - 1584

Views and Commentaries

Anaphase Promoting Complex or Cyclosome?

Duncan J. Clarke, Laura A. Díaz-Martínez and Juan F. Giménez-Abián
Volume: 4 | Issue: 11 | Pages: 1585 - 1592

Report1

Myeloid Leukemia-Associated Nucleophosmin Mutants Perturb p53-Dependent and Independent Activities of the Arf Tumor Suppressor Protein

Willem den Besten, Mei-Ling Kuo, Richard T. Williams and Charles J. Sherr
Volume: 4 | Issue: 11 | Pages: 1593 - 1598

Report

Impaired Phagocytosis in Caveolin-1 Deficient Macrophages

Jiangwei Li, Alexis Scherl, Freddy Medina, Philippe G. Frank, Richard N. Kitsis, Herbert B. Tanowitz, Federica Sotgia and Michael P. Lisanti
Volume: 4 | Issue: 11 | Pages: 1599 - 1607

High-Risk But Not Low-Risk HPV E2 Proteins Bind to the APC Activators Cdh1 and Cdc20 and Cause Genomic Instability

Sophie Bellanger, Stéphanie Blachon, Francisca Mechali, Catherine Bonne-Andrea and Françoise Thierry
Volume: 4 | Issue: 11 | Pages: 1608 - 1615

A Novel Role of p38α MAPK in Mitotic Progression Independent of Its Kinase Activity

Li Fan, Xianlin Yang, Jian Du, Mark Marshall, Kerry Blanchard and Xiang Ye
Volume: 4 | Issue: 11 | Pages: 1616 - 1624

Regulation of the Cyclin-Dependent Kinase Inhibitor p57Kip2 Expression by p63

Chiara Beretta, Anna Chiarelli, Barbara Testoni, Roberto Mantovani and Luisa Guerrini
Volume: 4 | Issue: 11 | Pages: 1625 - 1631

Novel Functional Features of the LIS-H Domain: Role in Protein Dimerization, Half-Life and Cellular Localization

Gabi Gerlitz, Enbal Darhin, Giovanna Giorgio, Brunella Franco and Orly Reiner
Volume: 4 | Issue: 11 | Pages: 1632 - 1640

BRCA1 Regulates Gene Expression for Orderly Mitotic Progression

Insoo Bae, Jeong Keun Rih, Hee Jeong Kim, Hyo Jin Kang, Bassem Haddad, Alexander Kirilyuk,, Saijun Fan, Maria L. Avantaggiati and Eliot M. Rosen
Volume: 4 | Issue: 11 | Pages: 1641 - 1666

ATR Activation Necessary But Not Sufficient for p53 Induction and Apoptosis in Hydroxyurea-Hypersensitive Myeloid Leukemia Cells

Sujatha Kumar, Gerald E. Dodson, Anthony Trinh, Joel R. Puchalski and Randal S. Tibbetts
Volume: 4 | Issue: 11 | Pages: 1667 - 1674

Constitutively Active Cdc42 Mutant Confers Growth Disadvantage in Cell Transformation

Cristina Vanni, Catherine Ottaviano, Fukun Guo, Maura Puppo, Luigi Varesio, Yi Zheng and Alessandra Eva
Volume: 4 | Issue: 11 | Pages: 1675 - 1682

Premeiotic Origin of Teratomas: Is Meiosis Required for Differentiation into Mature Tissues?

Zhengping Zhuang, Mojgan Devouassoux-Shisheboran, Irina A. Lubensky, Fattaneh Tavassoli and Alexander O. Vortmeyer
Volume: 4 | Issue: 11 | Pages: 1683 - 1687