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Table of Contents

october 2005

volume 4| issue 10



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Then Negative Regulation of Phosphoinositide 3-Kinase Signaling by p85 and Its Implication in Cancer

Ji Luo and Lewis C. Cantley
Volume: 4 | Issue: 10 | Pages: 1309 - 1312

ΔNp63α Levels Correlate with Clinical Tumor Response to Cisplatin

Rachel Zangen, Edward Ratovitski and David Sidransky
Volume: 4 | Issue: 10 | Pages: 1313 - 1315

The Arf Tumor Suppressor Regulates Platelet-Derived Growth Factor Receptor ? Signaling: A New View through the Eyes of Arf-/- Mice

J. Derek Thornton, Ricardo L.A. Silva, Amy C. Martin and Stephen X. Skapek
Volume: 4 | Issue: 10 | Pages: 1316 - 1319

Telomere Sister Chromatid Exchange in Telomerase Deficient Murine Cells

Yisong Wang, Richard J. Giannone and Yie Liu
Volume: 4 | Issue: 10 | Pages: 1320 - 1322

Human Embryonic Stem Cells as a Model for Studying Epigenetic Regulation During Early Development

Peter J. Rugg-Gunn, Anne C. Ferguson-Smith and Roger A. Pedersen
Volume: 4 | Issue: 10 | Pages: 1323 - 1326

Oncogenic Remodeling of the Three-Dimensional Organization of the Interphase Nucleus: c-Myc Induces Telomeric Aggregates Whose Formation Precedes Chromosomal Rearrangements

Sabine Mai and Yuval Garini
Volume: 4 | Issue: 10 | Pages: 1327 - 1331

Drosophila Female Meiosis and Embryonic Syncytial Mitosis Use Specialized Cks and CDC20 Proteins for Cyclin Destruction

Andrew Swan and Trudi Schüpbach
Volume: 4 | Issue: 10 | Pages: 1332 - 1334

The Oncoprotein Gankyrin Negatively Regulates Both p53 and RB by Enhancing Proteasomal Degradation

Hiroaki Higashitsuji, Yu Liu, R. John Mayer and Jun Fujita
Volume: 4 | Issue: 10 | Pages: 1335 - 1337

Self-Renewal of the Adult Skeletal Muscle Satellite Cell

Charlotte A. Collins and Terence A. Partridge
Volume: 4 | Issue: 10 | Pages: 1338 - 1341

Perspectives

The Two Faces of NF?B in Cell Survival Responses

Bonnie Graham and Spencer B. Gibson
Volume: 4 | Issue: 10 | Pages: 1342 - 1345

Monitoring the Cell Cycle by Multi-Kinase-Dependent Regulation of Swe1/Wee1 in Budding Yeast

Kyung S. Lee, Satoshi Asano, Jung-Eun Park, Krisada Sakchaisri and Raymond L. Erikson
Volume: 4 | Issue: 10 | Pages: 1346 - 1349

Colorectal Cancer Progression: Integrin alphavbeta6 and the Epithelial-Mesenchymal Transition (EMT)

Richard C. Bates
Volume: 4 | Issue: 10 | Pages: 1350 - 1352

Stem Cell Regulation by the Haemopoietic Stem Cell Niche

David N. Haylock and Susan K. Nilsson
Volume: 4 | Issue: 10 | Pages: 1353 - 1355

Mechanisms of Tumor Suppression by the SCFFbw7

Alex C. Minella and Bruce E. Clurman
Volume: 4 | Issue: 10 | Pages: 1356 - 1359

Cardiomyocyte Proliferation: A Platform for Mammalian Cardiac Repair

Felix B. Engel
Volume: 4 | Issue: 10 | Pages: 1360 - 1363

p16INK4a as a Second Effector of the Telomere Damage Pathway

Jacqueline J.L. Jacobs and Titia de Lange
Volume: 4 | Issue: 10 | Pages: 1364 - 1368

Biomarkers to Predict Response to Epidermal Growth Factor Receptor Inhibitors

Daphne A. Haas-Kogan, Michael D. Prados, Kathleen R. Lamborn, Tarik Tihan, Mitchel S. Berger and David Stokoe
Volume: 4 | Issue: 10 | Pages: 1369 - 1372

Dynamics of Chromatin during the Repair of DNA Double-Strand Breaks

Jessica A. Downs and Jacques Cote
Volume: 4 | Issue: 10 | Pages: 1373 - 1376

Towards the Human Cancer Epigenome: A First Draft of Histone Modifications

Mario F. Fraga and Manel Esteller
Volume: 4 | Issue: 10 | Pages: 1377 - 1381

Brief Report

Analysis of BRAF Mutation in Primary and Metastatic Melanoma

Massimo Libra, Grazia Malaponte, Patrick M. Navolanic, Pietro Gangemi, Valentina Bevelacqua, Lidia Proietti, Bibiana Bruni, Franca Stivala, Maria C. Mazzarino, Salvatore Travali and James A. McCubrey
Volume: 4 | Issue: 10 | Pages: 1382 - 1384

Low Concentrations of Taxol Cause Mitotic Delay Followed by Premature Dissociation of p55CDC from Mad2 and BubR1 and Abrogation of the Spindle checkpoint, Leading to Aneuploidy

Amy E. Ikui, Chia-Ping Huang Yang, Tomohiro Matsumoto and Susan Band Horwitz
Volume: 4 | Issue: 10 | Pages: 1385 - 1388

Report

Increased Protein Expression of the PTEN Tumor Suppressor in the Presence of Constitutively Active Notch-1

William H. Chappell, Thomas D. Green, Justin D. Spengeman, James A. McCubrey, Shaw M. Akula and Fred E. Bertrand
Volume: 4 | Issue: 10 | Pages: 1389 - 1395

Antisense Knockdown of Cyclin E does not affect the Midblastula Transition in Xenopus laevis Embryos

Michael K. Slevin, Gillian Lyons-Levy, Daniel L. Weeks and Rebecca S. Hartley
Volume: 4 | Issue: 10 | Pages: 1396 - 1402

Poliovirus Protein 3A Binds and Deregulates LIS1, Causing Block of Membrane Protein Trafficking and Deregulation of Cell Division

Anna A. Kondratova, Nickolay Neznanov, Roman V. Kondratov and Andrei V. Gudkov
Volume: 4 | Issue: 10 | Pages: 1403 - 1410

The N-terminal Regulatory Domain of Cyclin A Contains Redundant Ubiquitination Targeting Sequences and Acceptor Sites

Tsz Kan Fung, Cain H. Yam and Randy Y.C. Poon
Volume: 4 | Issue: 10 | Pages: 1411 - 1420

The Acidic Tail domain of Human Cdc34 is Required for p27Kip1 Ubiquitination and Complementation of a cdc34 Temperature Sensitive Yeast Strain

Karen Block, Srikanth Appikonda, Horng-Ru Lin, Joanna Bloom, Michele Pagano and P. Renee Yew
Volume: 4 | Issue: 10 | Pages: 1421 - 1427

Inhibition of the ATR/Chk1 Pathway Induces a p38-Dependent S-phase Delay in Mouse ES Cells

Ludmila Jirmanova, Dmitry V. Bulavin and Albert J. Fornace, Jr.
Volume: 4 | Issue: 10 | Pages: 1428 - 1434

Human Cytomegalovirus Inactivates the G0/G1-APC/C Ubiquitin Ligase by Cdh1 Dissociation

Lüder Wiebusch, Miriam Bach, Ralf Uecker and Christian Hagemeier
Volume: 4 | Issue: 10 | Pages: 1435 - 1439

AEC-Associated p63 Mutations Lead to Alternative Splicing/Protein Stabilization of p63 and Modulation of Notch Signaling

Yi-Ping Huang, Yuriy Kim, Zhaobo Li, Tanya Fomenkov, Alexey Fomenkov and Edward A. Ratovitski
Volume: 4 | Issue: 10 | Pages: 1440 - 1447

Spindle Checkpoint Maintenance Requires Ame1 and Okp1

Isabelle Pot, James Knockleby, Victoria Aneliunas, Thao Nguyen, Sonia Ah-Kye, Gregory Liszt, Michael Snyder, Philip Hieter and Jackie Vogel
Volume: 4 | Issue: 10 | Pages: 1448 - 1456