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Table of Contents

july 2004

volume 3| issue 7



Perspective1

Imatinib: Paradigm or Anomaly?

Brian J. Druker
Volume: 3 | Issue: 7 | Pages: 833 - 835

Open Access Article



Extra Views

p53 Moves to Mitochondria: A Turn on the Path to Apoptosis

Maureen E. Murphy, J. I-Ju Leu and Donna L. George
Volume: 3 | Issue: 7 | Pages: 836 - 839

Open Access Article


Does Cancer Solve an Optimization Problem?

Natalia Komarova
Volume: 3 | Issue: 7 | Pages: 840 - 844

Open Access Article


Life, Death, and E2F: Linking Proliferation Control and DNA Damage Signaling via E2F1

Harry A. Rogoff and Timothy F. Kowalik
Volume: 3 | Issue: 7 | Pages: 845 - 846

Open Access Article


Reversing Drug Resistance In Vivo

Hans-Guido Wendel and Scott W. Lowe
Volume: 3 | Issue: 7 | Pages: 847 - 849

Open Access Article


Don't Skip the G1 Phase: How APC/CCdh1 Keeps SCFSKP2 in Check

Tarig Bashir and Michele Pagano
Volume: 3 | Issue: 7 | Pages: 850 - 852

Open Access Article


Dynamic Balancing of the Dual Nature of HIF-1alpha for Cell Survival

Minori Koshiji and L. Eric Huang
Volume: 3 | Issue: 7 | Pages: 853 - 854

Open Access Article


A New Look at Rho GTPases in the Cell Cycle: Their Role in Kinetochore-Microtubule Attachment

Shuh Narumiya, Fabian Oceguera-Yanez and Shingo Yasuda
Volume: 3 | Issue: 7 | Pages: 855 - 857

Open Access Article


Interference of BCR-ABL1 Kinase Activity with Antigen Receptor Signaling in B cell Precursor Leukemia Cells

Florian Klein, Niklas Feldhahn and Markus Müschen
Volume: 3 | Issue: 7 | Pages: 858 - 860

Open Access Article


Cdc42p, GTP Hydrolysis and the Cell’s Sense of Direction

Javier E. Irazoqui, Amy S. Gladfelter and Daniel J. Lew
Volume: 3 | Issue: 7 | Pages: 861 - 864

Open Access Article



Perspectives

Stopped for Repairs: A New Role for Nutrient Sensing Pathways

Jennifer S. Searle and Yolanda Sanchez
Volume: 3 | Issue: 7 | Pages: 865 - 868

Open Access Article


Reprogramming RelA

Kirsteen J. Campbell and Neil D. Perkins
Volume: 3 | Issue: 7 | Pages: 869 - 872

Open Access Article


Sex Chromosomes and Male Functions: Where Do New Genes Go?

Esther Betrán, J.J. Emerson, Henrik Kaessmann and Manyuan Long
Volume: 3 | Issue: 7 | Pages: 873 - 875

Open Access Article


Control of Erythropoiesis by Erythropoietin and Stem Cell Factor: A Novel Role for Bruton’s Tyrosine Kinase

Marieke von Lindern, Uwe Schmidt and Hartmut Beug
Volume: 3 | Issue: 7 | Pages: 876 - 879

Open Access Article


Chromatin Turn Ons and Turn Offs of Ribosomal RNA Genes

Richard J. Lawrence and Craig S. Pikaard
Volume: 3 | Issue: 7 | Pages: 880 - 883

Open Access Article



Review

Introduction: p53 Regulation—A Family Affair

Ygal Haupt
Volume: 3 | Issue: 7 | Pages: 884 - 885

Open Access Article


p73 and p63: Why Do We Still Need Them?

Giovanni Blandino and Matthias Dobbelstein
Volume: 3 | Issue: 7 | Pages: 886 - 894

Open Access Article


Dynamics in the p53-Mdm2 Ubiquitination Pathway

Christopher L. Brooks and Wei Gu
Volume: 3 | Issue: 7 | Pages: 895 - 899

Open Access Article


Mdmx and Mdm2: Brothers in Arms?

Jean-Christophe Marine and Aart G. Jochemsen
Volume: 3 | Issue: 7 | Pages: 900 - 904

Open Access Article


KeePin’ the p53 Family in Good Shape

Fiamma Mantovani, Monica Gostissa, Licio Collavin and Giannino Del Sal
Volume: 3 | Issue: 7 | Pages: 905 - 911

Open Access Article


Improving Cancer Therapy through p53 Management

Susan Haupt and Ygal Haupt
Volume: 3 | Issue: 7 | Pages: 912 - 916

Open Access Article



Views and Commentaries

Medulloblastoma and Retinoblastoma: Oncology Recapitulates Ontogeny

Justyna T. Romer and Thomas Curran
Volume: 3 | Issue: 7 | Pages: 917 - 919

Open Access Article


Myc Tagging along the TRAIL to Death Receptor 5

M. Saeed Sheikh
Volume: 3 | Issue: 7 | Pages: 920 - 922

Open Access Article



Report

Human Ninein is a Centrosomal Autoantigen Recognized by CREST Patient Sera and Plays a Regulatory Role in Microtubule Nucleation

Elizabeth E. Stillwell, Jun Zhou and Harish C. Joshi
Volume: 3 | Issue: 7 | Pages: 923 - 930

Open Access Article


Induction of Transcription by p21Waf1/Cip1/Sdi1: Role of NF?B and Effect of Non-steroidal Anti-inflammatory Drugs

Jason C. Poole, Alison Thain, Neil D. Perkins and Igor B. Roninson
Volume: 3 | Issue: 7 | Pages: 931 - 940

Open Access Article


ATR, Claspin and the Rad9-Rad1-Hus1 Complex Regulate Chk1 and Cdc25A in the Absence of DNA Damage

Claus Storgaard Sørensen, Randi G. Syljuåsen, Jiri Lukas and Jiri Bartek
Volume: 3 | Issue: 7 | Pages: 941 - 945

Open Access Article


Physical and Functional Interactions between Mitotic Kinases during Polyploidization and Megakaryocytic Differentiation

Xuan Huang, Qin Ruan, Yuqiang Fang, Frank Traganos, Zbigniew Darzynkiewicz and Wei Dai
Volume: 3 | Issue: 7 | Pages: 946 - 951

Open Access Article


The First Knockout Mouse Model of Retinoblastoma

Jiakun Zhang, Brett Schweers and Michael A. Dyer
Volume: 3 | Issue: 7 | Pages: 952 - 959

Open Access Article


Cdc14p/FEAR Pathway Controls Segregation of Nucleolus in S. cerevisiae by Facilitating Condensin Targeting to rDNA Chromatin in Anaphase

Bi-Dar Wang, Vladimir Yong-Gonzalez and Alexander V. Strunnikov
Volume: 3 | Issue: 7 | Pages: 960 - 967

Open Access Article