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Table of Contents

december 2004

volume 3| issue 12



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Epithelial-Mesenchymal Transition: NF-κB Takes Center Stage

Margit A. Huber, Hartmut Beug and Thomas Wirth
Volume: 3 | Issue: 12 | Pages: 1477 - 1482

Regulation of Cell Cycle in Hematopoietic Stem Cells by the Niche

Atsushi Hirao, Fumio Arai and Toshio Suda
Volume: 3 | Issue: 12 | Pages: 1481 - 1484

Heat Shock Protein 70 Promotes Cancer Cell Viability by Safeguarding Lysosomal Integrity

Mads Gyrd-Hansen, Jesper Nylandsted and Marja Jäättelä
Volume: 3 | Issue: 12 | Pages: 1484 - 1485

Abl Oncogene Bypasses Normal Regulation of JAK/STAT Activation

André Limnander and Paul B. Rothman
Volume: 3 | Issue: 12 | Pages: 1486 - 1488

Delineating the Hepatocyte's Hematopoietic Fusion Partner

Holger Willenbring and Markus Grompe
Volume: 3 | Issue: 12 | Pages: 1489 - 1491

Stress-Induced p53 Runs a Direct Mitochondrial Death Program: Its Role in Physiologic and Pathophysiologic Stress Responses In Vivo

Susan Erster and Ute M. Moll
Volume: 3 | Issue: 12 | Pages: 1492 - 1495

Inhibition of Mutant EGF Receptors by Gefitinib: Targeting an Achilles’ Heel of Lung Cancer

Jeffrey Settleman
Volume: 3 | Issue: 12 | Pages: 1496 - 1497

Protein Phosphorylation as a Key Mechanism for the Regulation of BCL-3 Activity

Patrick Viatour, Marie-Paule Merville, Vincent Bours and Alain Chariot
Volume: 3 | Issue: 12 | Pages: 1498 - 1501

Pharmacokinetic Resistance to Imatinib Mesylate: Role of the ABC Drug Pumps ABCG2 (BCRP) and ABCB1 (MDR1) in the Oral Bioavailability of Imatinib

Herman Burger and Kees Nooter
Volume: 3 | Issue: 12 | Pages: 1502 - 1505

Perspectives

Red Light, Green Light: Signals That Control Endothelial Cell Proliferation during Embryonic Vascular Development

Brenda L. Bohnsack and Karen K. Hirschi
Volume: 3 | Issue: 12 | Pages: 1506 - 1511

Wnt and Cyclooxygenase-2 Cross-talk Accelerates Adenoma Growth

Dingzhi Wang, Jason R. Mann and Raymond N. DuBois
Volume: 3 | Issue: 12 | Pages: 1512 - 1515

Multiple Roles for Cysteine Cathepsins in Cancer

Johanna A. Joyce and Douglas Hanahan
Volume: 3 | Issue: 12 | Pages: 1516 - 1519

JNK2: A Negative Regulator of Cellular Proliferation

Kanaga Sabapathy and Erwin F.Wagner
Volume: 3 | Issue: 12 | Pages: 1520 - 1523

NF-κB and JNK: An Intricate Affair

Concetta Bubici, Salvatore Papa, Can G. Pham, Francesca Zazzeroni and Guido Franzoso
Volume: 3 | Issue: 12 | Pages: 1524 - 1529

Review

Hsp90 Activation and Cell Cycle Regulation

Francis Burrows, Hong Zhang and Adeela Kamal
Volume: 3 | Issue: 12 | Pages: 1530 - 1536

Flavopiridol, An Inhibitor of Transcription: Implications, Problems and Solutions

Mikhail V. Blagosklonny
Volume: 3 | Issue: 12 | Pages: 1537 - 1542

Report

p53 Prevents the Accumulation of Double-Strand DNA Breaks at Stalled-Replication Forks Induced by UV in Human Cells

Shoshana Squires, Julia A. Coates, Michal Goldberg, Lorraine H. Toji, Stephen P. Jackson, Duncan J. Clarke and Robert T. Johnson


Volume: 3 | Issue: 12 | Pages: 1543 - 1557

Initiation of Colorectal Cancer: Where do the Two Hits Hit?

Natalia L. Komarova and Liming Wang
Volume: 3 | Issue: 12 | Pages: 1558 - 1565

Pro- and Anti-Apoptotic Effects of an Inhibitor of Chymotrypsin-Like Serine Proteases

Malcolm A. King, Dorota Halicka and Zbigniew Darzynkiewicz
Volume: 3 | Issue: 12 | Pages: 1566 - 1571

Regulation of Cyclin E Protein Levels through E2F-Mediated Inhibition of Degradation

Deborah Pajalunga and Marco Crescenzi
Volume: 3 | Issue: 12 | Pages: 1572 - 1578

ATR and ATM-Dependent Movement of BLM Helicase during Replication Stress Ensures Optimal ATM Activation and 53BP1 Focus Formation

Albert R. Davalos, Patrick Kaminker, Rhonda K. Hansen and Judith Campisi
Volume: 3 | Issue: 12 | Pages: 1579 - 1586

Altered Sumoylation of p63α Contributes to the Split-Hand/Foot Malformation Phenotype

Yi-Ping Huang, Guojun Wu, Zhongmin Guo, Motonobu Osada,Tanya Fomenkov, Hannah Lui Park, Barry Trink, DavidSidransky, Alexey Fomenkov and Edward A. Ratovitski
Volume: 3 | Issue: 12 | Pages: 1587 - 1596

Genistein Induces G2 Arrest in Malignant B Cells by Decreasing IL-10 Secretion

Amal Mansour, Brian McCarthy, Stephan K Schwander, Victor Chang, Sergei Kotenko, Sreekrishna Donepudi, Janet Lee and Elizabeth Raveche
Volume: 3 | Issue: 12 | Pages: 1597 - 1605

Cell Death Inhibiting RNA (CDIR) Modulates IFN-γ-Stimulated Sensitization to Fas/CD95/Apo-1 and TRAIL/Apo-2L-Induced Apoptosis

Ksenya Shchors, Fruma Yehiely and Louis P. Deiss
Volume: 3 | Issue: 12 | Pages: 1606 - 1611

Comparative Genomics, Evolution and Origins of the Nuclear Envelope and Nuclear Pore Complex

Berend Mans, Vivek Anantharaman, L. Aravind and Eugene V. Koonin
Volume: 3 | Issue: 12 | Pages: 1612 - 1637

Ufd2, a Novel Autoantigen in Scleroderma, Regulates Sister Chromatid Separation

Sarah Spinette, Christoph Lengauer, James A. Mahoney, Prasad V. Jallepalli, Zhenghe Wang, Livia Casciola-Rosen and Antony Rosen
Volume: 3 | Issue: 12 | Pages: 1638 - 1644

A Dynamic Switch in the Replication Timing of Key Regulator Genes in Embryonic Stem Cells upon Neural Induction

Pascale Perry, Stephan Sauer, Nathalie Billon, William D. Richardson, Mikhail Spivakov, Gary Warnes, Frederick J. Livesey, Matthias Merkenschlager, Amanda G. Fisher and Véronique Azuara
Volume: 3 | Issue: 12 | Pages: 1645 - 1650