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Perspectives

Maintaining Youth in Drosophila Neural Progenitors

Takako Isshiki and Chris Q. Doe
Volume 3, Issue 3
March 2004
Pages 294 - 297

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An important question is how dividing stem cells maintain competence to generate multiple cell types, whereas most other cells become progressively restricted during development. The molecular basis for progenitor competence – or how competence is progressively restricted – has remained mysterious. Recent work has shown that Drosophila neuroblasts and mammalian neural progenitors are more similar than previously appreciated, and provide an excellent model system for using Drosophila genetics to unravel the molecular nature of progenitor competence and how it becomes progressively restricted during development


Authors

Takako Isshiki
Chris Q. Doe

We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:

 Download PDF

If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.

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