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Perspectives
Telomerase: Going Beyond the Ends
David De Semir, Mehdi Nosrati, Shang Li and Mohammed Kashani-Sabet
volume 6 | issue 5
1 March 2007Pages: 546 - 549
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To date, the major function attributed to telomerase has been the elongation of telomeres. Recent studies have assigned new biochemical properties to telomerase by implicating a role in tumor metastasis and cellular differentiation by virtue of its modulation of novel cell signaling pathways such as glycolysis. In this Perspective we will discuss these recent results that have provided additional insight into the involvement of telomerase in cellular processes other than telomere maintenance at chromosome ends.
Authors
David De Semir
University of California San Francisco
Mehdi Nosrati
University of California San Francisco
Shang Li
University of California San Francisco
Mohammed Kashani-Sabet
University of California San Francisco
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.