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Perspectives
Regulation, Cell Differentiation and Protein-Based Inheritance
Fabienne Malagnac and Phillippe Silar
volume 5 | issue 22
15 november 2006Pages: 2584 - 2587
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Recent research using fungi as models provide new insight into the ability of regulatory networks to generate cellular states that are sufficiently stable to be faithfully transmitted to daughter cells, thereby generating epigenetic inheritance. Such protein-based inheritance is driven by infectious factors endowed with properties usually displayed by prions. We emphasize the contribution of regulatory networks to the emerging properties displayed by cells.
Authors
Fabienne Malagnac
Institut de Génétique et Microbiologie, Université de Paris; Orsay, France
Phillippe Silar
Institut de Génétique et Microbiologie, Université de Paris; Orsay, France
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.