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Topoisomerase II Checkpoints: Universal Mechanisms that Regulate Mitosis
Duncan J. Clarke, Amit C. Vas, Catherine A. Andrews, Laura A. Díaz-Martínez and Juan F. Giménez-Abián
volume 5 | issue 17
1 september 2006Pages: 1925 - 1928
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Checkpoint controls confer order to the cell cycle and help prevent genome instability. Here we discuss the Topoisomerase II (Decatenation) Checkpoint which functions to regulate mitotic progression so that chromosomes can be efficiently condensed in prophase and can be segregated with high fidelity in anaphase.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.