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Perspectives
Controlling Stem Cell Proliferation: CKIs at Work
Sophia W.M. Bruggeman and Maarten van Lohuizen
volume 5 | issue 12
15 june 2006Pages: 1281 - 1285
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The cyclin-dependent kinase inhibitors or CKIs are well recognized as intrinsic regulators of the cell cycle. Here, we discuss recent data implicating their activity in restraining adult stem cell self-renewal, and the role that proteins regulating CKI expression play in this process.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.