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Identification of Novel ARF Binding Proteins by Two-Hybrid Screening
Van Tompkins, Jussara Hagen, Valerie P. Zediak and Dawn E. Quelle
volume 5 | issue 6
16 march 2006Pages: 641 - 646
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The ARF tumor suppressor protects us against cancer through protein-protein interactions in partially defined p53-dependent and p53-independent pathways. We performed a two-hybrid screen using ARF as bait and present the identification of several new ARF partners that may regulate its growth inhibitory signaling. The potential physiological roles of these novel ARF binding proteins in regulating ARF signaling are discussed.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.