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Perspectives
Akt1 in Endothelial Cell and Angiogenesis
Payaningal R. Somanath, Olga V. Razorenova, Juhua Chen and Tatiana V. Byzova
volume 5 | issue 5
1 march 2006Pages: 512 - 518
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Akt, also known as Protein kinase B (PKB), regulates essential cellular functions such as migration, proliferation, differentiation, apoptosis, and metabolism. Akt influences the expression and/or activity of various pro- and anti-angiogenic factors and Akt isoforms (Akt1, Akt2 and Akt3) have been proposed as therapeutic targets for angiogenesis-related anomalies such as cancer and ischemic injury.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.