Editorials: Cell Cycle Features

Too much or too little: Harnessing senescence to control oncogene-driven cancer

Volume 11, Issue 17   September 1, 2012
Pages 3147 - 3148
http://dx.doi.org/10.4161/cc.21588
Authors: Katherine M. Hannan and Richard B. Pearson

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Abstract:
Comment on: Astle MV, et al. Oncogene 2012; 31:1949-62.

Editorials: Cell Cycle Features to:
MV Astle, KM Hannan, PY Ng, RS Lee, AJ George, AK Hsu, Y Haupt, RD Hannan, RB Pearson. AKT induces senescence in human cells via mTORC1 and p53 in the absence of DNA damage: implications for targeting mTOR during malignancy. Oncogene 2012; 31: 1949-62
PMID: 21909130 DOI: 10.1038/onc.2011.394

Received: June 20, 2012; Accepted: June 25, 2012; Published Online: August 16, 2012

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