Sign up for Table of Contents Alerts.
Email this page
Print this page
Extra Views
Control of Cell Cycle Progression by the Stress-Activated Hog1 MAPK
Meritxell Zapater, Josep Clotet, Xavier Escoté and Francesc Posas
volume 4 | issue 1
january 2005Pages: 6 - 7
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.
Activation of the stress-activated Hog1 kinase is essential for cell survival in response to high osmolarity. The Hog1 SAPK elicits the program for cell adaptation that includes modulation of several aspects of cell biology, such as, gene expression, translation and cell-cycle progression. In response to stress, the Hog1 SAPK mediates a transient cell cycle arrest required for proper cell adaptation. A recent report has described the mechanism underlying the effect of the SAPK at G1. Here, we propose that the mechanisms that involve cell cycle control in response to osmostress are of great complexity and that they could be conserved among eukaryotic cells.
We now provide open access to journal articles published online for one year or more. This article may be downloaded at the following link:
Download PDF If the document does not open, please right-click on the link (control-click on a Macintosh) and select the option to save the file to disk.