MicroRNAs control herpesviral dormancy

Volume 9, Issue 7 April 1, 2010
Pages 1225 - 1226
http://dx.doi.org/10.4161/cc.9.7.11387

Xiufen Lei, Zhiqiang Bai, Fengchun Ye, Yufei Huang and Shou-Jiang Gao

View affiliations

Infections by herpesviruses are widespread in humans, and are the causes for several important diseases. Gammaherpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) is etiologically associated with Kaposi's sarcoma (KS), a highly inflammatory and angiogenic cancer commonly found in AIDS patients.1 KSHV is also associated with primary effusion lymphoma and a subset of multicentric Castleman’s disease, two rare lymphoproliferative malignancies.