Email this page

Print this page

Extra Views

ENY2: Couple, triple...more?

Daria V. Kopytova, Alexey N. Krasno, Anastasija V. Orlova, Dmitriy Ya. Gurskiy, Elena N. Nabirochkina, Sofia G. Georgieva and Yulii V. Shidlovskii

ENY2/Sus1, a protein involved in the coupling of transcription with mRNA export, is a component of SAGA/TFTC and TREX-2/AMEX complexes. Recently, we have described the association of ENY2 with the third protein complex, THO. Moreover, our data indicate that ENY2 is also associated with other factors, both in the nucleus and cytoplasm. Thus, being a shared components of several protein complexes, ENY2 appears to function as an adapter molecule involved in integration of cellular processes, in particular, subsequent stages of gene expression.

Authors

Daria V. Kopytova

Russian Academy of Sciences; Moscow, Russia

Alexey N. Krasno

Russian Academy of Sciences; Moscow, Russia

Anastasija V. Orlova

Russian Academy of Sciences; Moscow, Russia

Dmitriy Ya. Gurskiy

Russian Academy of Sciences; Moscow, Russia

Elena N. Nabirochkina

Russian Academy of Sciences; Moscow, Russia

Sofia G. Georgieva

Russian Academy of Sciences; Moscow, Russia

Yulii V. Shidlovskii Corresponding author: yul@genebiology.ru

Russian Academy of Sciences; Moscow, Russia